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[1]于静,胡永权,王贵花,等.四种中药对感染牙本质小管粪肠球菌的抑制作用[J].环球中医药,2012,5(01):23-0.
　YU Jing,HU Yong quan,WANG Gui hua,et al.Inhibiting effects of four Chinese medicinal herb on enterococcus faecalis in the infected root canals[J].,2012,5(01):23-0.
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四种中药对感染牙本质小管粪肠球菌的抑制作用()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第5卷
期数:
2012年01期
页码:
23-0
栏目:
论著
出版日期:
2012-01-06

文章信息/Info

Title:
Inhibiting effects of four Chinese medicinal herb on enterococcus faecalis in the infected root canals
作者:
于静; 胡永权; 王贵花; 戴东晓; 李君如; 谢景朝; 王荣霞; 赵发银;
Author(s):
YU Jing;  HU Yongquan;  WANG Guihua;  et al.
Department of Oral Medicine, the Second Hospital of Shijiazhuang City, Shijiazhuang 050051，China
关键词:
根管消毒;  粪肠球菌;  中药;  水煎剂;  抑菌效果
Keywords:
Root canal sterilizing; Enterococcus faecals; Chinese Medical Herb; Decoction; Bacteriostatic effect
分类号:
R781.33
DOI:
-
文献标志码:
A
摘要:
目的比较黄连等4种中药水煎剂对离体人牙根管内粪肠球菌的体外抑菌效果。方法选取84颗新鲜拔除的人单根管牙,截取6mm高的柱状牙根。随机分为4个实验组(黄连水煎剂组、五味子水煎剂组、大黄水煎剂组、连翘水煎剂组)和3个对照组[甲醛甲酚(FC)组、阴性对照组和阳性对照组],每组12颗牙。常规根管预备后灭菌制备感染粪肠球菌根管模型,阴性对照组不感染细菌,放置0.9%氯化钠注射液,余每组根管均感染细菌,分别放置上述不同药剂,3天、7天后分别培养并测量细菌的透光度。结果黄连水煎剂组3天与甲酫甲酚组3天组间无差别(P>0.05); 连翘水煎剂组3天与阳性对照组3天组间无差别(P>0.05); 五味子水煎剂组3天与阴性对照组7天组间无差别(P>0.05); 大黄水煎剂组3天、黄连水煎剂组7天与甲酫甲酚组7天组间无差别(P>0.05); 连翘水煎剂组7天与阳性对照组7天组间无差别(P>0.05); 其余各组间差别均有统计学意义(P<0.05)。结论四种中药中,黄连、五味子、大黄均有不同程度抑制粪肠球菌的作用,黄连作用最强。黄连抑菌作用与FC相同。连翘无抑制粪肠球菌的作用。
Abstract:
ObjectiveThe purpose of this study was to compare the inhibiting effects of four Chinese medicinal herb decoctions (such as Coptis chinensis Franch) on Enterococcus Faecals in the infected root canals. MethodsA total of 84 singlerooted extracted human teeth were used in this study.The teeth were randomly divided into four groups (Coptis chinensis Franch decoction group, Schisandra Chinensis decoction group, Chinese rhubarb decoction group and Frucrus forsythia decoction group) and three control groups (FC group, negative control group, and positive control group). Every group contained 12 teeth. The E. faecalis infected root canal models were manufactured after normal root canal preparation and sterilization. The teeth of negative control group was not infected by bacteria, and placed in 0.9% sodium chloride injection. The other teeth were infected by E. faecalis and treated with different Chinese medical herbs decoction separately. Transmittances of each group were measured after 3 days and 7 days. ResultsThere was no difference in the following comparisons, Coptis chinensis Franch decoction group (3 d) and FC group (3 d) comparison, Frucrus Forsythia decoction group (3 d) and positive control group (3 d) comparison, Frucrus Forsythia decoction group (3 d) and negative control group (7d) comparison, Chinese rhubarb decoction group (3 d), Coptis chinensis Franch decoction group (7 d) and FC group (7 d) comparison, Frucrus Forsythia (7 d) and positive control group (7 d) comparison, (P>005). There were statistical significance in the other groups. (P<0.05). ConclusionsIn the four Chinese medical herbs mentioned above, Coptis chinensis Franch, Schisandra Chinensis and Chinese rhubarb had inhibition effects on E. faecalis at different levels. Among the four Chinese medical herbs, the most powerful one was Coptis chinensis Franch, that has the same inhibition effects as FC. Frucrus Forsythia has no inhibition effects on E. faecalis.

参考文献/References:

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备注/Memo

备注/Memo:
基金课题：河北省2011年医学科学研究重点课题计划（20110184）
作者单位：050051 石家庄市第二医院口腔科（于静、胡永权、戴东晓、李君如、谢景朝、赵发银），检验科（王贵花、王荣霞）
作者简介：于静（1974－ ），女，硕士，副主任医师。研究方向：口腔临床医学。Email：zhangyifan991122@sina.com
更新日期/Last Update: 1900-01-01