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[1]刘新敏,刘睿,艾莉,等.基于血清异常激素的多囊卵巢综合征中医证候研究[J].环球中医药,2013,6(01):12-0.
　LIU Xin min,LIU Rui,AI li,et al.Research of polycystic ovarian syndrome TCM syndromes based on serum abnormal hormones[J].,2013,6(01):12-0.
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基于血清异常激素的多囊卵巢综合征中医证候研究()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第6卷
期数:
2013年01期
页码:
12-0
栏目:
论著
出版日期:
2013-01-06

文章信息/Info

Title:
Research of polycystic ovarian syndrome TCM syndromes based on serum abnormal hormones
作者:
刘新敏;刘睿;艾莉;文胜;周雪忠;马兰;李文;徐信;王燕;刘莹;李艳红;
Author(s):
LIU Xinmin; LIU Rui; AI li; et al.
Department of Gynecology，Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China.
关键词:
多囊卵巢综合征; 证候研究; 血清激素; 相关性
Keywords:
Polycystic ovary syndrome; TCM syndromes; Serum hormone; Correlation
分类号:
R271.9
DOI:
-
文献标志码:
A
摘要:
目的探讨多囊卵巢综合征(PCOS)血清异常激素与中医证候的相关性。方法记录240名多囊卵巢综合征患者的血清睾酮(T)、促黄体素(LH)、胰岛素、月经情况、症状、舌象、脉象等,进行中医辨证,分别统计异常激素的证候频次,用Logistic多元回归分析探讨异常血清激素与中医证候的相关性。结果纳入患者中出现频次最多的证候有四型,包括肝肾阴虚证、肾阴虚火旺证、肝胃郁热证、脾虚胃热证,其中,高睾酮出现频次最多的是肾阴虚火旺证,高促黄体素出现频次最多的是肝肾阴虚证,高胰岛素出现频次最多的是肝胃郁热证;高睾酮与肾阴虚火旺证、高促黄体素与肝肾阴虚证和肾阴虚火旺证、高胰岛素与肝胃郁热证和脾虚胃热证均呈显著正相关关系(P<0.01)。结论多囊卵巢综合征异常血清激素与证候有相关性,不同激素的中医病位不同。
Abstract:
ObjectiveTo investigate the correlation between abnormal serum hormones and TCM syndromes of polycystic ovarian syndrome(PCOS) . MethodsTCM syndromes of 240 cases of PCOS were carried out by questionaires including the level of serum testosterone, luteinizing hormone, insulin,symptoms, tongue picture, pulse condition, menstrual cycle, period, menstrual volume，color，blood clot，dysmenorrhoea，etal. The frequencies of each type of TCM syndromes were statisticed according to the abnormal serum hormones. Logistic multiple regression analysis was performed to analyze the correlation of abnormal serum hormones and TCM syndromes. ResultsThe most four TCM syndromes among the 240 patients are deficiency of liveryin and kidneyyin, kidneyyin deficiency and hyperactivity of fire, stagnated heat in liver and stomach, and deficiency of spleen and heat of stomach.The most TCM syndrome of high T patients was kidneyyin deficiency and hyperactivity of fire,which of high LH patients was deficiency of liveryin and kidneyyin and of high insulin was stagnated heat in liver and stomach. High T and kidneyyin deficiency and hyperactivity of fire, high LH and deficiency of liveryin and kidneyyin, high insulin and stagnated heat in liver and stomach and deficiency of spleen and heat of stomach showed significantly positive correlation relationship(P＜0.01). ConclusionAbnormal serum hormone had its relative TCM pathological position, and was associated with TCM syndrome.

参考文献/References:

［1］Homburg R.Androgen circle of polycystic ovary syndrome［J］.Human Reproduction,2009,24(7):15481555.
［2］赵君利，陈子江，赵力新，等.汉族育龄多囊卵巢综合征患者的临床特征及分析［J］.中华妇产科杂志，2006，41（6）：375379.
［3］马延敏，王树玉，贾婵维，等.异常月经周期与多囊卵巢综合征的相关性分析［J］.中国优生与遗传杂志，2010，18（8）：9799.
［4］赵冬妮，石玉华，陈子江.PCOS患者胰岛素抵抗的临床评价［J］.实用妇产科杂志，2010,26（8）：563566.
［5］倪仁敏，杨冬梓.胰岛素抵抗与PCOS代谢综合征［J］. 实用妇产科杂志，2010,26（8）：566568.
［6］Alviggi C,Clarizia R,Mollo A,et al.Outlook:who needs LH in ovarian stimulation?［J］. Reprod Biomed Online,2006,12(5):599607.
［7］Aboulghar M.Critical evaluation of the use LH［A］.In:Kruger TF,Spuy ZVD,Kempers RD(eds).Advances in fertility studies and reproduction medicine(IFFS) ［M］.Capetown:Juta & Co Ltd,2007:4451.
［8］张以文.多囊卵巢综合征的现代概念［J］.中华妇产科杂志,2004,39(9):577578.
［9］季绍良.中医诊断学［M］.北京:人民卫生出版社，2002:99174.
［10］郑筱萸.中药新药临床研究指导原则［M］.北京：中国医药科技出版社，2002.
［11］刘新敏，华强.从现代文献探讨多囊卵巢综合征的中医证候及证候要素分布特点［J］.中国中医药信息杂志，2011,18（2）：3436.
［12］姚乃礼.中医证候鉴别诊断学［M］.北京:人民卫生出版社，2002:103260.
［13］陈子江，刘嘉茵.多囊卵巢综合征基础与临床［M］.北京:人民卫生出版社，2009:98100.
［14］张志斌,王永炎.证候名称及分类研究的回顾与假设的提出［J］.北京中医药大学学报,2003，26(2): 15.

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金（81072839）；中国中医科学院优势病种课题（CACMS08Y006）
作者单位：100053北京，中国中医科学院广安门医院妇科（刘新敏、艾莉、文胜、王燕、刘莹、李艳红）；北京中医药大学针灸推拿学院[刘睿（硕士研究生）、马兰（硕士研究生）、李文（硕士研究生）、徐信（硕士研究生）]; 北京交通大学计算机与信息技术学院（周雪忠）
作者简介：刘新敏（1968- ），女，博士，副主任医师。研究方向：多囊卵巢综合征的临床与实验研究。Email：beijingliuxm@163.com
更新日期/Last Update: 1900-01-01