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[1]张喆,刘瑜,姜良铎,等.基于因子分析的胃食管反流性咳嗽的病机要素研究[J].环球中医药,2013,6(03):178-0.
　ZHANG Zhe,LIU Yu,JIANG Liang duo,et al.Study on pathological key factors of gastroesophageal reflux cough based on the factor analysis[J].,2013,6(03):178-0.
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基于因子分析的胃食管反流性咳嗽的病机要素研究()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第6卷
期数:
2013年03期
页码:
178-0
栏目:
论著
出版日期:
2013-03-06

文章信息/Info

Title:
Study on pathological key factors of gastroesophageal reflux cough based on the factor analysis
作者:
张喆;刘瑜;姜良铎;王微;符思;
Author(s):
ZHANG Zhe;  LIU Yu;  JIANG Liangduo;  et al.
Department of TCM Gastroenterology, ChinaJapan friendship hospital, Beijing 100029, China
关键词:
因子分析; 胃食管反流性咳嗽; 病机要素
Keywords:
Factor analysis; Gastroesophageal reflux cough; Pathological elements
分类号:
R256.3
DOI:
-
文献标志码:
A
摘要:
目的探索胃食管反流性咳嗽的病机要素。方法收集83例胃食管反流性咳嗽病例的症状、体征等资料,建立数据库,应用因子分析的方法进行统计分析,并结合临床知识给予解释确定病机要素。结果共得到9个公因子,累计贡献率78.305%,胃食管反流性咳嗽主要病因为体虚,病位主要在肺胃,与肝相关性较强,核心病机要素为肺胃同病,体虚蕴邪,气机升降失和,上逆致咳。结论因子分析是客观分析胃食管反流性咳嗽的病机要素的有效方法之一,其病机核心为肺胃蕴邪,气机上逆。
Abstract:
ObjectiveTo explore pathological key factors of gastroesophageal reflux cough (GERC). Methods The data such as symptoms, signs, and other data was collected in 83 patients with gastroesophageal reflux cough. It was entered into the database and analyzed by the statistical methods of factor analysis. Then it was interpreted with the traditional Chinese medical knowledge to determine the elements of pathogenesis of GERC. ResultsNine common factors were obtained and the accumulative contribution rate of them was 78305% by studying. The cause of GERC was deficiency. It was located on Lung and Stomach and was related with Liver. The pathological core of GERC was adverse rising of Qi because of out of harmony of ascending and descending due to accumulated pathogenic Qi in Lung and Stomach in the deficiency body. ConclusionFactor analysis was one of objective effective methods on exploring pathological elements of GERC, the core is adverse rising of Qi due to accumulated pathogenic Qi in Lung and Stomach.

参考文献/References:

［1］Novitsky YW, Zawacki JK, Irwin RS, et al. Chronic cough due to gastroesophageal reflux disease: efficacy of antireflux surgery[J]. Surgical Endoscopy, 2002, 16(4): 567571.
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［5]郑筱萸．中药新药临床研究指导原则[M]．北京：中国医药科技出版社，2002．
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备注/Memo

备注/Memo:

作者单位：100029 北京，卫生部中日友好医院中医消化科（张喆、刘瑜、王微、符思）；北京中医药大学附属东直门医院（姜良铎）
作者简介：张喆（1980- ），博士，主治医师。研究方向：中西医结合治疗消化系统疾病。Email：zhangzhebj@yahoo.com.cn
通讯作者：符思（1957- ），本科，主任医师。研究方向：中西医结合治疗消化系统疾病。Email：fusizryh@yahoo.cn
更新日期/Last Update: 1900-01-01