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[1]陈思兰 李桂芹 高冬梅.补肾健脾疏肝方治疗桥本氏甲状腺炎的临床 研究[J].环球中医药,2013,6(04):245-248.
　CHEN Si lan,LI Gui qin,GAO Dong mei..Clinical studies of reinforcing kidney and strengthening spleen and soothing liver prescription on treating Hashimotos thyroiditis[J].,2013,6(04):245-248.
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补肾健脾疏肝方治疗桥本氏甲状腺炎的临床 研究()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第6卷
期数:
2013年04期
页码:
245-248
栏目:
论著
出版日期:
2013-04-06

文章信息/Info

Title:
Clinical studies of reinforcing kidney and strengthening spleen and soothing liver prescription on treating Hashimotos thyroiditis
作者:
陈思兰 李桂芹 高冬梅
作者单位：100053 北京，中国中医研究院广安门医院内分泌科（陈思兰）；北京中医药大学针灸推拿学院(李桂芹、高冬梅)
Author(s):
CHEN Silan;  LI Guiqin;  GAO Dongmei.
Department of Endocrinology, Guang anmen Hospital, China
Academy of Chinese Medical Sciences, Beijing 100053, China
Corresponding author: CHEN Silan, Email: CSL2196@126.com
关键词:
桥本氏甲状腺炎; 亚临床甲状腺功能减退; 中西医结合治疗; 补肾健脾疏肝方
Keywords:
Hashimotos thyroiditis; Subclinical hypothyroidism; Clinical studies; Reinforcing kidney and strengthening spleen and soothing liver Prescription
分类号:
R581.4
DOI:
-
文献标志码:
-
摘要:
目的观察自拟补肾健脾疏肝方联合小剂量优甲乐治疗桥本氏甲状腺炎继发亚临床甲状腺机能减退患者的疗效。方法将50例此类患者随机分为两组，对照组口服左甲状腺素钠每天 25 ug，治疗组在此基础上加服中药补肾健脾疏肝方。两组均以3个月为一疗程，共治疗二个疗程。结果在中医证候总疗效，中医证候积分神疲乏力、畏寒肢冷、便溏、急躁易怒症状以及甲状腺功能指标：促甲状腺激素（thyroid stimulating hormone，TSH）和免疫指标：血清甲状腺过氧化物酶抗体（thyroid peroxidase antibody, TPOAb）、甲状腺球蛋白抗体（thyroglobulin antibody, TgAb）方面，治疗组均明显优于对照组（P＜0.05）。结论补肾健脾疏肝方治疗桥本氏甲状腺炎继发亚临床甲减有较好疗效。
Abstract:
ObjectiveTo probe into the efficacy of the “reinforcing kidney and strengthening spleen and soothing liver prescription” in treating the Hashimotos thyroiditis concomitant subclincal hypothyroidism. Methods50 diagnosed Hashimotos thyroiditis concomitant subclinical hypothyroidism patients were randomly divided into two groups on the principle of randomized control in clinical trials. The control group was treated by taking levothyroxine sodium(LT4Na) orally (25 μg per day); the treatment group was treated by taking reinforcing kidney and strengthening spleen and soothing liver prescription orally one dose per day as supplement to the LT4Na taken orally. Two courses of treatment each lasting three month were given to both groups. ResultsIn terms of TCM syndrome efficacy assessment, TCM syndrome score assessments such as the lassitude, intolerance to cold, cold hands and feet, loose stool, irascibility, and thyroid stimulating hormone level as well as thyroid autoantibodies TPOAb and TGAb, when compared between the groups, the treatment group was associated with better efficacy (P＜0.05). Conclusionreinforcing kidney and strengthening spleen and soothing liver prescription proved to have an excellent treatment effect to the Hashimotos thyroiditis concomitant subclinical hypothyroidism.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目：中国中医科学院名医名家传承项目（CM20121003)；中国中医科学院优势病种研究项目（CACMS08Y003）
作者简介：陈思兰（1962- ），女，本科，副主任医师。研究方向：内分泌疾病基础与临床。Email: CSL2196@126.com
更新日期/Last Update: 2013-04-30