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[1]许卫华 王微 吕冉 符思.大柴胡汤合茵陈蒿汤加减配合西药治疗急性 胆源性胰腺炎的临床研究[J].环球中医药,2013,6(04):249-252.
　XU Wei hua,WANG Wei,Lv Ran,et al.Efficacy of Dachaihu and Yinchenhao decoction combined with medicine in patients with acute biliary pancreatitis[J].,2013,6(04):249-252.
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大柴胡汤合茵陈蒿汤加减配合西药治疗急性 胆源性胰腺炎的临床研究()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第6卷
期数:
2013年04期
页码:
249-252
栏目:
论著
出版日期:
2013-04-06

文章信息/Info

Title:
Efficacy of Dachaihu and Yinchenhao decoction combined with medicine in patients with acute biliary pancreatitis
作者:
许卫华 王微 吕冉 符思
作者单位：100029北京，卫生部中日友好医院中医消化科
Author(s):
XU Weihua;  WANG Wei;  Lv Ran;  et al.
Department of TCM Gastroenterology, China
Japan Friendship Hospital, Beijing 100029, China
Corresponding auther: FU Si, Email: fusibj57@yahoo.com.cn
关键词:
急性胆源性胰腺炎; 大柴胡汤合茵陈蒿汤; 临床疗效
Keywords:
Acute biliary pancreatitis; Dachaihu decoction and Yinchenhao Decoction; Efficacy; Safety
分类号:
R657.5+1
DOI:
-
文献标志码:
-
摘要:
目的探讨大柴胡汤合茵陈蒿汤加减配合常规西药的方法治疗急性胆源性胰腺炎的临床疗效。方法收集56例急性胆源性胰腺炎的患者，随机分为西药对照组（给予常规西药抑酸、抑制胰酶、抗感染、补液等治疗）和中西医结合治疗组（大柴胡汤合茵陈蒿汤加减配合常规西药治疗）各28例，比较两组患者的临床疗效、症状缓解时间，比较两组患者血淀粉酶、尿淀粉酶、脂肪酶等实验室指标，并观测两组不良反应发生情况，运用SPSS 16.5统计软件进行分析。结果经秩和检验分析，中西医结合治疗组比西药对照组疗效好，P＜0.05；中西医结合治疗组腹胀缓解时间、腹痛缓解时间和首次排便时间较对照组显著缩短，经t检验P＜0.05，差异有统计学意义；两组治疗前后血淀粉酶、尿淀粉酶、脂肪酶、白细胞计数、C-反应蛋白均显著下降，经t检验P＜0.05；但比较中西医结合治疗组与西药对照组治疗后这些实验室指标，无显著性差异，经t检验P＞0.05。结论大柴胡汤合茵陈蒿汤加减配合西药治疗急性胆源性胰腺炎可以有效改善急性胆源性胰腺炎患者的临床症状，缩短患者恢复时间，安全有效。
Abstract:
ObjectiveTo study the efficacy and safety of Dachaihu decoction and Yinchenhao decoction and addition with medicine in patients with acute biliary pancreatitis. MethodsA total of 56 patients of acute biliary pancreatitis (ABP) were recruited in the randomized trial. The efficacy and safety of Dachaihu decoction and Yinchenhao decoction and addition with medicine were assessed by symptoms, physical and laboratory examination. ResultsThe efficacy of the treatment group was better than control group and had significant difference, (P＜0.05). The time of abdominal pain and abdominal bloating relief, and the first defecation time in treatment group were significantly shorten than those of control group, (P＜0.05). The blood amylase, urine amylase, blood lipase, leukocyte, and Creactive protein of two groups were all significantly decreased between the two groups. But there were no significant difference between two group after treatment (P＞0.05). Two case had nausea and vomiting after oral administration of traditional Chinese Medicine and disappeared by enema. ConclusionAs a safety and effective combination, Dachaihu and Yinchenhao decoction combined with medicine can remarkably relief symptoms and improve lab index in treating patients with ABP.

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备注/Memo

备注/Memo:
作者简介：许卫华（1977- ），女，硕士，主治医师。研究方向：中西医结合治疗消化系统疾病 Email: xuwihua10@163.com
通讯作者：符思（1957- ），主任医师，教授，硕士生导师，中国中西医结合学会老年病专业委员会常务委员，世界中医药学会联合会消化病专业委员会理事。研究方向：中医药治疗消化系统疾病。Email: fusibj57@yahoo.com.cn
更新日期/Last Update: 2013-04-30