|本期目录/Table of Contents|

[1]朱晓晨 郭蓉娟 王嘉麟 邢佳 王椿野.抑郁症相关性失眠的证候要素及临床症状特点 研究[J].环球中医药,2013,6(05):325-328.
　ZHU Xiao chen,GUO Rong juan,WANG Jia lin,et al.Clinical characteristics and TCM syndrome elements in the depressive insomnia[J].,2013,6(05):325-328.
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抑郁症相关性失眠的证候要素及临床症状特点 研究()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第6卷
期数:
2013年05期
页码:
325-328
栏目:
论著
出版日期:
2013-05-06

文章信息/Info

Title:
Clinical characteristics and TCM syndrome elements in the depressive insomnia
作者:
朱晓晨 郭蓉娟 王嘉麟 邢佳 王椿野
作者单位：100078，北京中医药大学东方医院脑病二科
Author(s):
ZHU Xiaochen;  GUO Rongjuan;  WANG Jialin;  et al.
Dongfang Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100078, China
Corresponding author：GUO Rongjuan, Email：dfgrj@yahoo.cn
关键词:
抑郁症; 失眠; 证候要素
Keywords:
Depression; Insomnia; Syndrome elements
分类号:
R2777
DOI:
-
文献标志码:
-
摘要:
目的本研究通过对抑郁症相关性失眠和抑郁症不伴失眠两组患者进行中医证候要素观察，探索抑郁症相关性失眠患者证候要素分布规律及特点，并分析抑郁症相关性失眠患者证候要素与失眠形式之间的关系。方法本实验共纳入符合标准的抑郁症相关性失眠组患者100例和抑郁症不伴失眠患者50例，自拟中医证候要素观察表，对两组患者临床症状进行观察，比较两组患者证候要素特点，统计抑郁症相关性失眠患者失眠形式特点，并进一步观察抑郁症相关性失眠患者证候要素与失眠形式间是否存相关性。结果研究结果表明，抑郁症相关性失眠患者中主要的中医证候要素依次为“气虚”、“气滞”、“火热”、“阴虚”、“血虚”、“痰证”（发生均大于50%）。两组患者在中医证候要素“阴虚”对比时存在明显差异（P＜001）。经相关性检验提示抑郁症相关性失眠患者中医证候要素“气虚”与“早醒”呈显著正相关性（P＜001）。结论抑郁症相关性失眠的患者较其他抑郁症患者存在明显的“阴虚”表现。抑郁症相关性失眠中医证候要素“气虚”与失眠形式中早醒表现相关。
Abstract:
ObjectiveThe study mainly observes the distribution law on syndrome elements of patients with depressive insomnia by statistic elements of Traditional Chinese Medicine (TCM) syndrome in the group on depressive insomnia and the group on depression without insomnia. Then it analyzes the relationship between patients with depressive insomnia and the types of insomnia. MethodsThis experiment included 100 patients with depressive insomnia and 50 patients with noninsomnia depression. To test all patients with selfobservation to be elements of TCM syndrome observed information table, clinical symptoms in two groups of patients were observed. Compared elements of TCM syndrome between two groups. Then it statistics types features of insomnia of the patients with depressive insomnia. And further it observed whether or not exists a correlation between elements of TCM syndrome and types features of insomnia of the patients with depressive insomnia. ResultsThe results show that the major elements of TCM syndrome in depressive insomnia patients in order to “Qi deficiency”, “Qi stagnation”, “Fire syndrome”, “Yin deficiency”, “Xue deficiency”, “Phlegm syndrome” (Probability＞50%). Between the two groups, the “Yin deficiency” shows significantly different when comparing (P＜001). The Spearman correlation test shows that “Qi deficiency” and the insomnia in the end of sleep (early waking) are significantly positively correlated (P＜001). ConclusionThe patients with depressive insomnia have obvious “Yin deficiency” than the other depressive patients. The “Qi deficiency” maybe has important relationship with insomnia symptoms in the early awakening among the patients with depressive insomnia.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目：国家“十一五”科技支撑计划重点项目（2009BAI77B00）；国家自然科学基金(81072717)；北京中医药大学创新团队项目(2011CXTD23)
作者简介：朱晓晨（1985- ），女，硕士，住院医师。研究方向：中医情志疾病。Email: zxc_flyingsky@126.com
通讯作者：郭蓉娟（1964- ），女，博士，主任医师，博士生导师。研究方向：中药防治脑病基础及临床研究。Email: dfgrj@yahoo.com.cn
更新日期/Last Update: 2013-05-31