[1]王昌儒.基于厚朴七物汤及其母方对大鼠胃分泌功能的影响探讨合方的思想[J].环球中医药,2013,6(08):593-0.
WANG Chang ru..According the influence of Houpo Qiwu Decoction and its mother prescription on the function of rats， stomach to study compound prescription[J].,2013,6(08):593-0.
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基于厚朴七物汤及其母方对大鼠胃分泌功能的影响探讨合方的思想(
)
WANG Chang ru..According the influence of Houpo Qiwu Decoction and its mother prescription on the function of rats， stomach to study compound prescription[J].,2013,6(08):593-0.
)《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]
- 卷:
- 第6卷
- 期数:
- 2013年08期
- 页码:
- 593-0
- 栏目:
- 论著
- 出版日期:
- 2013-08-06
文章信息/Info
- Title:
- According the influence of Houpo Qiwu Decoction and its mother prescription on the function of rats， stomach to study compound prescription
- 作者:
- 王昌儒;
- Author(s):
- WANG Changru.
- Hubei University of Chinese Medicine,Wuhan 450065，China
- Keywords:
- Compound prescription; Houpo Sanwu Decoction; Houpo Qiwu Decoction; Guizhi Qushaoyao Decoction
- 分类号:
- R289
- DOI:
- -
- 文献标志码:
- A
- 摘要:
- 目的通过对厚朴七物汤与原母方间在功效上是否有相加、协同或拮抗作用的探讨,揭示"合方"中方与方间在主要功效方面可能存在的"增效"或"拮抗"关系。方法采用药理学方法,结合中药方剂的配合理论原则对厚朴七物汤及其母方厚朴三物汤与桂枝去芍药汤进行分析。结果桂枝去芍药汤与厚朴三物汤合方后,在保护胃黏膜方面,桂枝去芍药汤对厚朴三物汤产生了"增效"作用;桂枝去芍药汤与厚朴三物汤相合组成的厚朴七物汤,"先合后煎"的效果要优于"先煎后合"。结论桂枝去芍药汤减轻了厚朴三物汤对大鼠胃黏膜的损伤作用,即桂枝去芍药汤对厚朴三物汤的毒副作用是"相杀"关系,仲景合方中有"七情合和"的思想。
- Abstract:
- ObjectiveTo study the additive effect, synergismor antagonism between Houpo Sanwu Decoction and Guizhi Qushaoyao Decoction in their compound prescription so as to confirm the possible pharmacodynamic actions (similar to seven actions related to compatibility of ingredients in compound prescription). MethodsUsing the method of pharmacology and the principle of“seven actions related to compatibility offing redients in a prescription”of Chinese herbal medicine, the mutual effects between“Houpo Sanwu Decoction and Guizhi Qushaoyao Decoction in their compound prescription was studied.Results The research revealed that the combination of Houpo Sanwu Decoction and Guizhi Qushaoyao Decoction is more effective protection in gastric mucosa. ConclusionGuizhi Qushaoyao Decoction mitigate Houpo Sanwu Decoction injury of gastric mucosa ,this is “xiangsha”,In Zhangzhongjing,s compound prescriptions have the idea of “Qiqinghehe”.
参考文献/References:
［1］谢观. 中国医学大辞典［M］.北京：中国中医药出版社，1994：1005.
［2］李飞. 方剂学［M］. 北京：人民卫生出版社，2002：58.
［3］耿建国. 《伤寒杂病论》合方运用探讨［J］.南京中医药大学学报(自然科学版)，2000，16(2)：7173.
［4］徐淑云. 药理实验方法学［M］.北京：人民卫生出版社，1985：849.
［5］贾春华. 合方散论［J］.辽宁中医杂志，2003，30(8)：627628.
［6］任国峰. 仲景合方的理论研究与应用［D］.济南：山东中医药大学，2012.
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备注/Memo
- 备注/Memo:
-
作者单位：450065武汉，湖北中医药大学［王昌儒（博士研究生）］；商丘市第一人民医院中医科(王昌儒)
作者简介：王昌儒(1972- )，2011级在读博士研究生。研究方向：中医药防治内分泌疾病。Email：wcr369@163.com
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