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[1]何敏 周浴 邝军等.扶正抗癌方联合化疗治疗非小细胞肺癌疗效研究[J].环球中医药,2014,7(04):278-0.
　HE Min,ZHOU Yu,KUANG Jun,et al.Research of centralizer anticancer prescription combined chemotherapy in the treatment of nonsmall cell lung cancer[J].,2014,7(04):278-0.
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扶正抗癌方联合化疗治疗非小细胞肺癌疗效研究()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第7卷
期数:
2014年04期
页码:
278-0
栏目:
论著
出版日期:
2014-04-06

文章信息/Info

Title:
Research of centralizer anticancer prescription combined chemotherapy in the treatment of nonsmall cell lung cancer
作者:
何敏 周浴 邝军等
Author(s):
HE Min;  ZHOU Yu;  KUANG Jun;  et al.
Department 1 of Respiratory Medicine, Peoples Hospital affiliated to Hubei University of Medicine, Shiyan 442000, China
关键词:
扶正抗癌方:6369; 非小细胞肺癌:6117; 化疗治疗:3617; 疗效研究:2692; 联合:1288
Keywords:
The centralizer anticancer prescription; Nonsmall cell lung cancer; Chemotherapy
分类号:
R7342
DOI:
-
文献标志码:
A
摘要:
目的探讨扶正抗癌方联合化疗治疗非小细胞肺癌的临床疗效。方法对本院2006年7月至2012年6月住院非小细胞肺癌患者67例，按照随机数字表法分为治疗组33例和对照组34例，对照组采用化疗治疗，治疗组在对照组基础上使用扶正抗癌方治疗，治疗2个周期后，观察两组临床疗效、中医症候积分、Karnofsky功能状态评分标准（KPS）评分、毒副反应情况。结果近期临床疗效比较：治疗组有效率为3636%（12/33），对照组有效率为2352%（8/34），两组有效率比较不具有统计学意义（χ2=0776，P＞005）。中医症状积分改善情况及KPS改善情况比较：治疗组中医症候积分和KPS评分较治疗前有明显改善，与治疗前比较，具有显著性差异（P＜005）；治疗后治疗组症状积分及KPS评分明显优于对照组，具有统计学意义（P＜005或001）。毒副反应发生情况比较：治疗组恶心呕吐、口腔黏膜炎、肝损害、白细胞减少发生例数明显少于对照组，两组比较具有统计学意义（P＜001或P＜005）。结论化疗联合扶正抗癌方能缓解非小细胞肺癌患者临床症状，提高患者的生活质量，降低化疗的不良反应。
Abstract:
ObjectiveObjective To explore the centralizer anticancer prescription combined chemotherapy in the treatment of nonsmall cell lung cancer. Methods 67 cases of hospitalized patients with nonsmall cell lung cancer were randomly divided into treatment group according to admission order from July 2006 to June 2012, (33 cases and the control group, 34 cases in the control group with chemotherapy treatment, the treatment group on the basis of the control group using centralizer anticancer prescription, after two cycles, observe clinical effect and TCM symptom score, Karnofsky functional score(KPS) and adverse reaction conditions. ResultsThe comparison of recent clinical curative effect: the treatment group effective rate was 3636% (12/33), the control effective rate was 2352% (8/34), two groups of efficient was not statistically significant（P＜005）；the symptoms integral and KPS score of treatment group was better than control group, with statistical significance (P<005 or 001) .The adverse reaction comparison: the treatment group nausea and vomiting, inflammation of the oral mucosa, liver damage and white blood cells reduce was significantly less than the control group, the number of cases in the two groups are statistically significant (P<001 or 005). Conclusioncentralizer anticancer prescription combined chemotherapy can alleviate clinical symptoms in patients with nonsmall cell lung cancer, improve the quality of life of patients and reduce the adverse reaction of chemotherapy.

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备注/Memo

备注/Memo:

作者单位：442000 十堰，湖北医药学院附属人民医院呼吸内科一病区
作者简介：何敏（1979），女，硕士，主治医师。研究方向：呼吸内科。Email：hemin1437@sina.com
通讯作者：周浴（1979）,硕士，主治医师。研究方向:医学影像。Email：zhouyu9701@163.com
更新日期/Last Update: 1900-01-01