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[1]许卫华 王微 吕冉等.加味三香汤治疗肝郁脾虚型功能性消化不良的临床观察[J].环球中医药,2014,7(06):437-0.
　XU Wei hua,WANG Wei,LYU Ran,et al.Clinical study of Jiawei Sanxiang decoction treatment on patients with functional dyspepsia of liver stagnancy and spleen deficiency type[J].,2014,7(06):437-0.
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加味三香汤治疗肝郁脾虚型功能性消化不良的临床观察()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第7卷
期数:
2014年06期
页码:
437-0
栏目:
论著
出版日期:
2014-06-06

文章信息/Info

Title:
Clinical study of Jiawei Sanxiang decoction treatment on patients with functional dyspepsia of liver stagnancy and spleen deficiency type
作者:
许卫华 王微 吕冉等
Author(s):
XU Weihua;  WANG Wei;  LYU Ran;  et al
TCM gastroenterology department of ChinaJapan Friendship Hospital, Beijing 100029, China
关键词:
加味三香汤; 功能性消化不良; 肝郁脾虚证
Keywords:
Jiawei Sanxiang Decoction; Functional dyspepsia; Liver stagnancy and spleen deficiency type
分类号:
R25632
DOI:
-
文献标志码:
A
摘要:
目的观察中药加味三香汤治疗肝郁脾虚型功能性消化不良的临床疗效以及对焦虑、抑郁状态的影响。方法本研究采用随机、对照方法研究，共收集81例患者，随机分为治疗组与对照组。治疗组给予中药加味三香汤治疗，对照组给予西药复方消化酶治疗，疗程28天，对患者治疗前后的症状积分、Zung焦虑自评量表（selfrating anxiety scale, SAS）、抑郁自评量表（selfrating depression scale, SDS）积分进行统计分析。结果14天有效率治疗组与对照组无显著性差异（667%与640%，P＞005）；28天有效率治疗组显著高于对照组（882%与680%，P＜005）；治疗组与对照组治疗28天后症状积分较治疗前均显著减少（P＜005），治疗前后症状积分、餐后饱胀积分、早饱积分下降程度治疗组与对照组比较有显著性差异（P＜005）。焦虑、抑郁评分方面：治疗组治疗28天后SAS、SDS积分较治疗前均显著下降（P＜005）；治疗组SAS、SDS积分下降程度显著高于对照组（P＜005）。安全性评价两组均无严重不良反应。结论加味三香汤治疗肝郁脾虚型功能性消化不良具有良好的疗效及安全性，并可改善患者焦虑、抑郁状态。
Abstract:
ObjectiveTo explore the efficacy of Jiawei Sanxiang Decoction and the influence on anxious and depressive state of liver stagnancy and spleen deficiency type of functional dyspepsia(FD). MethodsA randomized controlled trials was conducted. 81 cases of FD patients were recruited and divided into treatment group and control group. Treatment group was treated with Jiawei Sanxiang Decoction, control group was treated with Compound Digestive Enzyme Capsules for 28 days. The symptom score, selfrating anxiety scale(SAS), selfrating depression scale(SDS) were analyzed before and after treatment. ResultsThere was no significant difference between treatment group and control group(667% vs. 640%)after 14 days of treatment (P＞005). However, there was significant difference between treatment group and control group after 28 days of treatment (882% vs 680%, P＜005).The symptom score in both groups were significantly decreased after 28 days of treatment (P＜005). The symptom score, postprandial fullness score, early satiety score of treatment group were significantly decreased compared to control group (P＜005) after 28 days of treatment. The SAS, SDS score were both significantly decreased in treatment group compare to baseline, the score of treatment group was significant decreased compare to control group. There was no severe side effect in both treatment group and control group. ConclusionsJiawei Sanxiang Decoction in the treatment of liver stagnancy and spleen deficiency type of functional dyspepsia is safe and effective, the anxious and depressive state of FD patients can be improved.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目：中日友好医院院级课题（2013MS04）
作者单位：100029 北京，中日友好医院中医消化科
作者简介：许卫华（1977 ），女，博士，主治医师。研究方向：中西医结合治疗消化系统疾病。Email: xuwihualo@163.com
通讯作者：符思（1957 ），本科，主任医师，教授，硕士生导师。研究方向：中医药治疗消化系统疾病。Email: fusibj57@aliyun.com
更新日期/Last Update: 1900-01-01