|本期目录/Table of Contents|

[1]邢佳,王嘉麟,贺立娟,等.补肾调肝法治疗老年期抑郁的疗效探讨[J].环球中医药,2015,8(04):432-435.[doi:10.3969/j.issn.1674-1749.2015.04.012]
　XING Jia,WANG Jia-lin,HE Li-juan,et al.Efficacy of tonifying kidney and supplementing liver therapy for senile depression[J].,2015,8(04):432-435.[doi:10.3969/j.issn.1674-1749.2015.04.012]
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补肾调肝法治疗老年期抑郁的疗效探讨()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第8卷
期数:
2015年04期
页码:
432-435
栏目:
论著
出版日期:
2015-04-06

文章信息/Info

Title:
Efficacy of tonifying kidney and supplementing liver therapy for senile depression
作者:
邢佳; 王嘉麟; 贺立娟; 张志辰; 孙玉爽; 郭蓉娟
作者单位:100078 北京中医药大学东方医院脑病二科
Author(s):
XING Jia;  WANG Jia-lin;  HE Li-juan;  et al.
NO.2 Department of Encephalopathy, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China Corresponding author:XING Jia, E-mail:dfyyxingjia@163.com
关键词:
老年抑郁症;  肾虚肝郁证;  盐酸舍曲林
Keywords:
Senile depression;  Kidney deficiency and liver qi stagnation syndrome;  Sertraline
分类号:
R277.7
DOI:
10.3969/j.issn.1674-1749.2015.04.012
文献标志码:
A
摘要:
目的 探讨补肾调肝法治疗老年期抑郁的临床疗效。方法 以肾虚肝郁型老年期抑郁患者为研究对象,分别采用补肾调肝汤(自拟)加减干预方案及西药盐酸舍曲林口服干预方案,观察期为12周,通过汉密尔顿抑郁量表减分率及中医证候疗效指数判断补肾调肝法对肾虚肝郁型老年期抑郁的临床疗效。结果 治疗12周前后补肾调肝汤和盐酸舍曲林组,在汉密尔顿抑郁量表、汉密尔顿焦虑量表、匹兹堡睡眠质量指数及肾虚肝郁量表均有下降(P<0.01); 其中对于汉密尔顿抑郁量表减分率的改善补肾调肝组不如盐酸舍曲林组,但对于汉密尔顿焦虑量表、匹兹堡睡眠质量指数及肾虚肝郁量表的减分率优于盐酸舍曲林组(P<0.01)。结论 补肾调肝法治疗老年期抑郁症具有良好的临床疗效,且具有改善睡眠及躯体症状的作用。
Abstract:
Objective To investigate the clinical efficacy of Tonifying Kidney and Supplementing Liver therapy for senile depression. Methods Bushen tiaogan(Tonifying Kidney and Supplementing Liver)Decoction, along with Western medicine and sertraline hydrochloride treatment, has been used for 12 weeks on senile depression patients of kidney deficiency and liver qi stagnation type. Clinical efficacy was assessed by the Hamilton Depression Scale(HAMD)score index and the rate of TCM syndrome curative effects.Results After 12 weeks of treatment, the index of HAMA, HAMD, PSQI as well as the scale of kidney deficiency and liver qi stagnation were reduced in both groups(P<0.01). Although the rate of reduction of HAMD in Bushen tiaogan Decoction group was not better than that in sertraline hydrochloride group, the rate of reduction of HAMA, PSQI, kidney deficiency and liver qi stagnation scale in Bushen tiaogan Decoction group was not better than that in sertraline hydrochloride group(P<0.01). Conclusion Bushen tiaogan therapy has good clinical efficacy for the treatment of senile depression, and it can also improve the quality of sleep and relieve somatic symptoms.

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备注/Memo

备注/Memo:
基金项目:2010年北京中医药大学东方医院院级课题(YJ201002); 2012年教育部博士点新教师类基金(20120013120014); 2013年北京中医药大学科研基金青年教师专项 作者简介:邢佳(1983- ),女,硕士,主治医师。研究方向:中医脑病。E-mail:dfyyxingjia@163.com
更新日期/Last Update: 2015-04-20