|本期目录/Table of Contents|

[1]乔佛晓,禹玉洪,李燕.荜茇的药理作用与毒性作用研究概述[J].环球中医药,2015,8(04):507-512.[doi:10.3969/j.issn.1674-1749.2015.04.038]
　QIAO Fo-xiao,YU Yu-hong,LI-Yan..Overview of pharmacological action and toxic effects of Piper Longum[J].,2015,8(04):507-512.[doi:10.3969/j.issn.1674-1749.2015.04.038]
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荜茇的药理作用与毒性作用研究概述()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第8卷
期数:
2015年04期
页码:
507-512
栏目:
综述
出版日期:
2015-04-06

文章信息/Info

Title:
Overview of pharmacological action and toxic effects of Piper Longum
作者:
乔佛晓; 禹玉洪; 李燕
作者单位:101111 北京,亚宝药业集团亚宝药业北京药物研究院(乔佛晓、禹玉洪); 中国医学科学院协和药物研究所(乔佛晓、李燕)
Author(s):
QIAO Fo-xiao;  YU Yu-hong;  LI-Yan.
Beijing Pharmaceutical Research Institute of Yabao pharmaceutical, Yabao Pharmaceutical Group co., LTD, Beijing 101111, China Corresponding author:LI-Yan, E-mail:yanli@imm.ac.cn; YU Yu-hong, E-mail:yyh100218@sohu.com
关键词:
荜茇;  化学成分;  药理作用;  安全性
Keywords:
Piper longum L.;  Chemical constituents;  Pharmacological effects;  Safety profile
分类号:
R285.5
DOI:
10.3969/j.issn.1674-1749.2015.04.038
文献标志码:
A
摘要:
由于不良反应较少,中草药在人类健康中的应用越来越多。用于治疗各种疾病的传统中草药数以万计。在这些中草药中,胡椒科植物在治疗人类多种疾病中具有重要作用。荜茇作为传统中草药至今还用于治疗各类疾病如:抗癌、保肝、抗氧化、抗炎、免疫调节、扩张冠状动脉血管、抗菌、抗血小板、抗生育、抗高血脂、减肥、止痛、杀虫、辐射防护、抑制黑色素生成、保护心肌、抗抑郁、抗真菌、抗阿米巴等药理学作用。荜茇及主要有效成分胡椒碱、荜茇环碱和荜茇宁的安全性较好。本文主要综述荜茇的植物化学、药理学作用及安全性方面的研究进展。由于荜茇具有中药的商业、经济及药用价值,对荜茇的详细研究非常有意义。
Abstract:
Chinese herbal medicine is used more and more in human health, due to fewer adverse reactions. Thousands of plants have been used traditionally to treat various diseases. Among them, plants in Pipraceae play an important role in the treatment of many human diseases.Piper longum L.,as a traditional Chinese herbal medicine, so far has been used for the treatment of various diseases such as: cancer, protecting liver, anti-oxidant, anti-inflammatory and immune regulation, dilating the coronary vessels, anti-bacterial, anti-platelet, anti-hyperlipidemic, relieving pain, insecticidal, protecting radiation, inhibiting melanin generation, protecting myocardial, anti-depression, anti-fungal, anti-amiba and other pharmacological effect. Piper longum L. and its main active components piperine and piperlonguminine have better safety. This study provides detailed information about the Piper longum L., including phytochemistry, pharmacological profile and safety profile. In view of the commercial, economic, and medicinal importance of the Piper longum L., it is useful for researchers to study the plant in detail.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金(2011ZX09201-201); 山西省基础研究项目(2011011035-5) 作者简介:乔佛晓(1985-),女,博士,副研究员。研究方向:药理学和药物代谢动力学。E-meil:qiaofoxiao1985@163.com 通讯作者:李燕(1954-),女,博士,研究员,博士生导师。研究方向:肝脏分子药理学和药物代谢动力学。E-mail:yanli@imm.ac.cn; 禹玉洪(1972-),博士,研究员。研究方向:中药制剂。 E-mail:yyh100218@sohu.com。李燕、禹玉洪并列为本文通讯作者。
更新日期/Last Update: 2015-04-20