|本期目录/Table of Contents|

[1]张成 赵志付 李健.心身疾病“刚柔辨证冶四种证候与脑电慢波改变的相关性研究[J].环球中医药,2015,8(08):916-920.[doi: doi:10.3969/j.issn.1674-1749.2015.08.006]
　ZHANG Cheng,ZHAO Zhi-fu,LI Jian..Research on relationship of four common syndromes of ‘Rigid-Gentle Syndrome Differentiation' of psychosomatic diseases and δ and θ wave change in brain electrical activity mapping[J].,2015,8(08):916-920.[doi: doi:10.3969/j.issn.1674-1749.2015.08.006]
点击复制

心身疾病“刚柔辨证冶四种证候与脑电慢波改变的相关性研究()
     
分享到：

《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第8卷
期数:
2015年08期
页码:
916-920
栏目:
论著
出版日期:
2015-08-06

文章信息/Info

Title:
Research on relationship of four common syndromes of ‘Rigid-Gentle Syndrome Differentiation' of psychosomatic diseases and δ and θ wave change in brain electrical activity mapping
作者:
张成 赵志付 李健
100053 中国中医科学院广安门医院心身医学科
Author(s):
ZHANG Cheng;  ZHAO Zhi-fu;  LI Jian.
Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
关键词:
心身疾病;  证候;  刚柔辨证;  脑电地形图;  δ波;  θ波
Keywords:
Psychosomatic diseases;  Syndrome;  Rigid-gentle syndrome differentiation;  Brain electrical activity mapping(BEAM);  δ wave;  θ Wave
分类号:
R749.92
DOI:
doi:10.3969/j.issn.1674-1749.2015.08.006
文献标志码:
A
摘要:
目的 通过观察心身疾病患者脑电信号慢波δ和θ波的功率值改变,探究心身疾病“刚柔辨证”四种常见证候与脑电慢波改变的相关关系。方法 “证病结合”“以方测证”为研究方法,采用脑电地形图为技术手段,把经显效方剂对应治疗2～8周后疗效为显效和临床痊愈的“刚柔辨证”主证为心肝火旺、心肝阴虚、肝郁气滞、肝郁脾虚证的患者治疗前脑电信号δ和θ波功率值与健康人对照组脑电信号δ和θ波功率值进行对照分析。其中心肝火旺证20例、心肝阴虚证32例、肝郁气滞证27例、肝郁脾虚证21例和健康人对照组23例。结果 心肝阴虚证与正常人对照组比较,δ波在额区和额极区功率值增高(在FP1、F3、F4,P<0.005; 在FP2,P<0.05),θ波在除了双颞区之外所有10个脑区功率值增高(P<0.005)。心肝火旺证、肝郁气滞证、肝郁脾虚证与正常人对照组比较,δ波和θ波功率值增高,以前头部为主,但此三组与对照组比较未见显著性差异。结论 初步揭示 “刚柔辨证”四种常见证候与脑电慢波改变的规律性及特异性表现,初步从脑电生理学角度揭示“刚柔辨证”理论的物质基础和证候实质。
Abstract:
Objective To explore the relationship of four common syndromes of ‘Rigid-Gentle Syndrome Differentiation' of psychosomatic diseases and δ and θ wave change in brain electrical activity mapping(BEAM). Methods Syndromes are the core while diseases are the complement. The accuracy of Syndrome Differentiation has been verifying by the curative effects of fixed traditional Chinese medicine(TCM)prescription. Each case was summarized by curative effects according to efficacy standards of different diseases. BEAM was used as technical means. Each case has been measured by BEAM before treatment. 100 cases of the four syndromes of ‘Hyperactivity of heart-fire and liver-fire', ‘Heart and liver yin deficiency', ‘Stagnation of QI due to depression of the liver' and ‘Stagnation of liver-QI with deficiency of the spleen' which belong to the system of ‘Rigid-Gentle Syndrome Differentiation' were enrolled in this study, and in order the number of cases are 20, 32, 27 and 21. In addition, the control group is of 23 healthy volunteers. Results The syndrome of ‘Heart and liver yin deficiency': the rising trend of δ wave power in frontal pole and frontal region(P<0.005 in FP1, F3, F4 and P<0.05 in FP2)and θ wave power in ten cortical areas except double temporal region(P<0.005). The syndrome of ‘Hyperactivity of heart-fire and liver-fire', ‘Stagnation of QI due to depression of the liver' and ‘Stagnation of liver-QI with deficiency of the spleen': the rising trend of slow wave power including δ wave and θ wave in forebrain, but no significant change compared with the control group. Conclusions This study has preliminarily demonstrated the regularities and specificities of slow wave change of four common syndromes of ‘Rigid-Gentle Syndrome Differentiation' compared with control group in BEAM. This study has preliminarily provided the evidences of the material bases and the nature of ‘Rigid-Gentle Syndrome Differentiation' of psychosomatic medicine from the aspects of BEAM.

参考文献/References:

[1] 张成,赵志付.心身医学研究新手段:脑电非线性分析[J].环球中医药,2013,6(3):218-221.
[2] 赵志付.浅析心身疾病的刚柔辨证[J].中医杂志,2006,47(2):146-147.
[3] 赵志付.心身疾病的病证结合临床研究—心身疾病的刚柔辨证[J].中国中西医结合杂志,2011,31(10):1304-1305.
[4] 赵志付,李健.中医心身医学:时代中医药临证之路[J].环球中医药,2013,6(1): 51-52.
[5] 国家中医药管理局.GB/T 16751.2-1997 中医临床诊疗术语证候部分[S].北京:国家技术监督局,1997.
[6] 国家中医药管理局.ZY/T001.4-94.3 中医病证诊断疗效标准[S].南京:南京大学出版社,1994.
[7] 郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002.
[8] 刘蕾,郭淑贞,王伟.中医证候研究的现状及发展趋势[J].中华中医药杂志,2008,23(8):661-663.
[9] 程昭寰,王永炎.论证候理论的科学性及其研究的关键间题[J].新中医,2006,38(7):7-9.
[10] 袁长津.辨证论治的内涵及其发展[J].湖南中医杂,2011,27(3):44-45.
[11] 朱克俭,黄一九.常见病中医证候流行病学调研思路[J].中国医药学报,1999,14(1):62-64.
[12] 袁曙光.方药中五步辨证论治法[J].光明中医杂志,1994,(1):34.
[13] 刘晓燕.临床脑电图学[M].北京:人民卫生出版社,2006:69-124.
[14] 大熊辉雄.脑电图判读step by step[M].北京:科学出版社,2001:69-112.
[15] 侯沂.脑电图在精神疾病中的应用[M].北京人民卫生出版社,2008:157-160.

相似文献/References:

[1]陈颖,崔英子,邓悦,等.冠状动脉粥样硬化性心脏病中医证候特征的文献回顾分析[J].环球中医药,2012,5(12):889.
　CHEN Ying,CUI Ying-zi,DENG Yue..Retrospectively the literatures of coronary heart disease syndrom of traditional Chinese medicine[J].,2012,5(08):889.
[2]韦衮政 韦爱欢 王现 石聪颖 万春平 张馨予 祁向荣.肺胀病常见证候的变化规律探讨[J].环球中医药,2015,8(07):814.[doi: doi:10.3969/j.issn.1674-1749.2015.07.014]
[3]孙旭,程培育,杨国旺,等.肺癌中医证候标准化研究[J].环球中医药,2015,8(12):1519.[doi:10.3969/j.issn.1674.1749.2015.12.032]
　SUN Xu,CHENG Pei-yu,YANG Guo-wang,et al.Study on standardization of TCM syndromes of lung cancer[J].,2015,8(08):1519.[doi:10.3969/j.issn.1674.1749.2015.12.032]
[4]赵进喜,贾海忠,王暴魁,等.抓病机,识体质,应对无症可辨; 察舌脉,重微观,丰富中医诊法[J].环球中医药,2016,9(01):41.[doi:10.3969/j.issn.1674-1749.2016.01.0010]
[5]常静玲 王爱琴 李胜利 卫冬洁 张庆苏 汪洁 高颖.中医综合康复干预下中风后失语的中医证候及临床症状演变探究[J].环球中医药,2016,9(08):1020.[doi:10.3969/j.issn.1674-1749.2016.08.039]
[6]王志斌 李军祥 余轶群 陈建新.基于因子分析及复杂系统熵聚堆法的酒精依赖症中医证候研究[J].环球中医药,2016,9(10):1161.[doi:10.3969/j.issn.1674-1749.2016.10.001]
　WANG Zhi-bin,LI Jun-xiang,YU Yi-qun,et al.Study of TCM syndrome characteristics of ADS based on factor analysis and complex system entropy cluster[J].,2016,9(08):1161.[doi:10.3969/j.issn.1674-1749.2016.10.001]
[7]张成,李健,赵志付.证病结合的证候研究模式符合心身疾病的基本特征[J].环球中医药,2016,9(12):1463.[doi:10.3969/j.issn.1674-1749.2016.12.006]
　ZHANG Cheng,LI Jian,ZHAO Zhi-fu..The syndrome study mode of‘Combination of syndromes and diseases' conforms to basic characteristics of psychosomatic diseases[J].,2016,9(08):1463.[doi:10.3969/j.issn.1674-1749.2016.12.006]
[8]韩桂玲,韩春生,张纾难,等.痰热郁肺型慢性阻塞性肺疾病急性加重期患者证候特点及理化指标的Logistic回归分析[J].环球中医药,2017,10(04):393.[doi:10.3969/j.issn.1674-1749.2017.04.003]
　HAN Guiling,HAN Chunsheng,ZHANG Shunan,et al.Logistic regression analysis on symptoms and physicochemical indexes in AECOPD patients with heat phlegm obstructing lung syndrome[J].,2017,10(08):393.[doi:10.3969/j.issn.1674-1749.2017.04.003]
[9]郝娟,周扬,邢枫,等.原发性胆汁性胆管炎的中医证候分析[J].环球中医药,2017,10(12):1438.[doi:10.3969/j.issn.1674-1749.2017.12.005]
　HAO Juan,ZHOU Yang,XING Feng,et al.Analysis of TCM syndrome of primary biliary cholangitis[J].,2017,10(08):1438.[doi:10.3969/j.issn.1674-1749.2017.12.005]

备注/Memo

备注/Memo:
作者简介:张成(1980- ),博士,主治医师。研究方向:中医心身医学。E-mail:zchgrace@163.com 通讯作者:赵志付(1950- ),博士,主任医师,教授,博士生导师。中华中医药学会内科分会委员,北京中医药学会心身医学专业委员会主任委员。研究方向:中医心身医学理论与临床。E-mail:tcmzzf@gmail.com
更新日期/Last Update: 1900-01-01