[1]蔡悦萍,张贵君,武亚楠,等.哈蟆油匀浆水溶液抗疲劳作用研究[J].环球中医药,2015,8(11):1337-1339.[doi:10.3969/j.issn.1674-1749.2015.11.016]
CAI Yue ping,ZHANG Gui jun,WU Ya nan,et al.Study on the anti fatigue effect of oviductus ranae homogenate solution[J].,2015,8(11):1337-1339.[doi:10.3969/j.issn.1674-1749.2015.11.016]
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哈蟆油匀浆水溶液抗疲劳作用研究(
)
《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]
- 卷:
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第8卷
- 期数:
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2015年11期
- 页码:
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1337-1339
- 栏目:
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论著
- 出版日期:
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2015-11-06
文章信息/Info
- Title:
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Study on the anti fatigue effect of oviductus ranae homogenate solution
- 作者:
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蔡悦萍; 张贵君; 武亚楠; 渠磊; 郑婧; 高晓美; 王道君
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蔡悦萍(1984- ),女,2009级在职硕士研究生。研究方向:中药鉴定方法研究。Email:lovingcyp@126.com
- Author(s):
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CAI Yueping; ZHANG Guijun; WU Yanan; et al.
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School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China
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- 关键词:
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哈蟆油; 抗疲劳; 血清尿素; 肝糖原; 血乳酸
- Keywords:
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Oviductus Ranae; Antifatigue; Serum urea; Glycogen; Blood lactate
- 分类号:
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R285.5
- DOI:
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10.3969/j.issn.1674-1749.2015.11.016
- 文献标志码:
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A
- 摘要:
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目的研究哈蟆油的抗疲劳作用。方法制备0.5% g/mL哈蟆油匀浆水溶液,采用小鼠灌胃给药,按成人日摄入量的1、10、30倍(即0.3、3.3、10.0 mL/kgBW)连续灌胃30天,与阴性对照组比较,测定负重小鼠游泳后血清尿素、肝糖原和血乳酸的含量。结果10.0 mL/kgBW剂量组能延长小鼠负重游泳时间,减少小鼠游泳时血清尿素和血乳酸的产生,与阴性对照组比较均有显著性差异(P<0.05)。结论成人每天服用20 mL的0.5% g/mL哈蟆油匀浆水溶液(0.1 g 哈蟆油)有明显的抗疲劳作用。
- Abstract:
-
ObjectiveTo study the antifatigue effect of Oviductus Ranae. MethodsThe Oviductus Ranae homogenate solution 0.5% g/mL was prepared,the mice were orally administered the drug into stomach at doses that 1,10 and 30 times the average adult amount of to adult(0.3,3.3,10 mL/kgBW) for 30 days, and then loaded them before determining the level of serum urea, liver glycogen and blood lactic acid.The results between intervention and control groups were then compared.ResultsMice from 10 mL/kgBW dose group exhibited a prolonged the swimming time,and reduced blood urea nitrogen and blood lactic acid production levels.These differences were statistically significant between intervention the control groups(P<005).Conclusion0.5% g/mL of Oviductus Ranae homogenate solution serves antifatigue effects in mice.
参考文献/References:
[1]常乐,刘汶,张琳.哈蟆油的研究进展[J].沈阳药科大学学报,2011,28(5):350409.
[2]]刘郁,刘连新.林蛙油的成分及药理研究进展[J].海峡药学,2007,19(12):13.
[3]]王涵,赵雨,张梅.哈蟆油降血脂、耐缺氧和抗疲劳的功能研究[J].食品研究与开发,2012,33(8):201203.
[4]]张梅,赵雨,杨士慧.哈蟆油抗疲劳药理活性研究[J].现代预防医学,2012,39(8):19781979.
[5]]李津明,宋茜,孙仁爽.林蛙油酶解前后抗疲劳作用对比研究[J].黑龙江医药,2008,21(2):3034.
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更新日期/Last Update:
1900-01-01