|本期目录/Table of Contents|

[1]乔雪,卓燊,杨子明,等.千斤拔属植物化学成分及药理作用的国内外研究进展[J].环球中医药,2015,8(12):1546-1549.[doi:10.3969/j.issn.1674.1749.2015.12.038]
　QIAO Xue,ZHUO Shen,YANG Zi-ming,et al.Chemical constituents and pharmacological effects of plant Flemingia[J].,2015,8(12):1546-1549.[doi:10.3969/j.issn.1674.1749.2015.12.038]
点击复制

千斤拔属植物化学成分及药理作用的国内外研究进展()
     
分享到：

《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第8卷
期数:
2015年12期
页码:
1546-1549
栏目:
综述
出版日期:
2015-12-06

文章信息/Info

Title:
Chemical constituents and pharmacological effects of plant Flemingia
作者:
乔雪; 卓燊; 杨子明; 秦海洸
530001 南宁,广西中医药大学[乔雪(硕士研究生)]; 广西科技大学医学院(卓燊、秦海洸); 广西植物功能物质研究与利用重点实验室 广西植物研究所(杨子明)
Author(s):
QIAO Xue;  ZHUO Shen;  YANG Zi-ming;  et al.
Guangxi University of Traditional Chinese Medicine, Nanning 530001, China
关键词:
千斤拔;  化学成分;  药理作用
Keywords:
Flemingia Roxb.ex Rottl;  Chemical composition;  Pharmacological effects
分类号:
R285
DOI:
10.3969/j.issn.1674.1749.2015.12.038
文献标志码:
A
摘要:
千斤拔属植物在中国一直作为民族药及民间药被广泛使用,其中有六种有确切药用历史,在中医上此属植物具有祛风除湿、强筋壮骨、消炎止痛、舒筋活络等功效,在临床上可用于治疗跌打损伤、腰腿痛、乳房疾病、牙痛及妇科病等。近年来国内外学者发现此属植物中含有糖类、黄酮类、氨基酸、甾体、生物碱、挥发油等其他化学成分,且具有类雌激素及抗雌激素样作用,以及良好的抗炎、抗血栓、抗氧化、镇痛、对神经系统损伤的保护等生物活性。本文通过查阅相关文献资料,对近年来国内外所研究的千斤拔属植物的化学成分及药理作用进行综述,为此属植物进一步研究,临床应用及新药开发提供参考。
Abstract:
The plants of Flemingia Roxb.ex Rottl have been widely used as a national medicine and folk medicine in our country since antiquity, six of which have an exact and long history of medicinal use. In Traditional Chinese medicine, the plants of Flemingia Roxb.ex Rottl have the effects of dispelling wind and removing dampness from the body, strengthening the sinews and the bones, diminishing inflammation and relieving pain, stimulating the circulation of the blood and causing the muscles and joints to relax. Clinically, they can be used to treat the injuries from fall, fractures, contusions and strains, pain in the waist and lower extremities, breast diseases, toothaches and gynecological diseases, etc. Recently, scholars both home and abroad found that the plants of Flemingia Roxb.ex Rottl contain such chemical components as sugars, flavonoids, amino acids, steroids, alkaloids, and volatile oils, etc. In addition, the plants of Flemingia Roxb.ex Rottl are anti-estrogenic effect and have the effects similar to xenoestrogen. Moreover, they are anti-inflammatory, antithrombotic, antioxidative and analgesic and have protective effects on nervous system injury. In this review, we summarize the chemical components and pharmacological effects of the Flemingia Roxb.ex Rottl, derived from our analysis of high-quality studies home and abroad and review of the literature on the Flemingia Roxb.ex Rottl, in the hope of providing reference for its further study, clinical application and development of new drugs in the future.

参考文献/References:

[1] 韦裕宗.中国千斤拔属植物的初步研究[J].广西植物.1991,11(3):198-204.
[2] 中华人民共和国卫生部药典委员会.中华人民共和国药典附录[S].北京:人民卫生出版社,1977.
[3] 吴征镒.新华本草纲要[M].上海科学技术出版社.1991.
[4] 陈元,杨世丁.千斤拔的临床应用[J].中国民族民间医药杂志,2001,(6):363.
[5] 黄艳菲,丁玲,李艳丹,等.三种千斤拔的化学成分预分析和薄层鉴定[J].西南民族大学学报,2011,37(4): 603-605.
[6] 李华,杨美华,马小军.千斤拔黄酮类化学成分研究[J].中国中药杂志,2009,34(6): 724-726.
[7] 李华,杨美华,斯建勇,等.千斤拔化学成分研究[J].中草药,.2009,40(4):512-516.
[8] 王小庆,杨树德,杨竹雅.蔓性千斤拔挥发性成分的研究[J].云南中医学院学报,2008,31(6):12-14.
[9] Eun-Mi Ahn,Norio Nakamura,Teruaki Akao,et al.Estrogenic and Antiestrogenic Activities of the Roots of Moghania philippinensis and TheirConstituents[J].Biol.Pharm.Bull,2004,27(4):548-553.
[10] 李宝强,宋启示.大叶千斤拔根的化学成分[J].中草药,2009,40(2):179-182.
[11] Varam R S,Parthasarathy M R.Triterpenoida and phthalates esler of Moghania macrophylla stem-bark[J].Curr.Sci,1976,45(22):797.
[12] 李丹毅,富艳彬.蔓性千斤拔根的化学成分研究[J].中草药,2012,43(7): 1259-1262.
[13] 孙琳,李占林,韩国华,等.千斤拔化学成分研究[J].中国药物杂志,2009,19(5):363-367.
[14] 曾春兰,卢文杰,牙启康,等.大叶千斤拔脂溶性成分分析[J].广西科学,2011,18(2):151-152,157.
[15] Wang Y,Curtis-Long MJ.Inhibition of tyrosinase activity by polyphenol compounds from Flemingia philippinensis roots[J].Bioorg Med Chem, 2014,22(3):15-20.
[16] Wang Y,Curtis-Long MJ.Bacterial neuraminidase inhibitory effects of prenylated soflavones from roots of Flemingia philippinensis[J].Bioorg Med Chem,2013,21(21):398-404.
[17] 付鑫,吕春平,金明华,等.千斤拔对高脂血症大鼠一氧化氮及一氧化氮合酶的影响[J].中国实验诊断学,2011,15(7):1059-1060.
[18] 张明秋,关铭,年晓莉,等.千斤拔黄酮抑制血栓形成机制研究[J].中国老年学杂志,2009,29(16):2074-2076.
[19] 赵节绪,尹长江,林世和,等.千斤拔对实验性蛛网膜下腔出血急性期脑组织及血脑屏障的保护作用[J].白求恩医科大学学报,1997,23(5):489-491.
[20] Gahlot K,Lal VK,Jha S.Anticonvulsant potential of ethanol extracts and their solvent partitioned fractions from Flemingia strobilifera root[J]. Pharmacongnosy Res,2013,5(4):265-270.
[21] 陈一,李开双,黄凤娇.千斤拔的镇痛和抗炎作用[J].广西医学,1993,15(2):77-79.
[22] Ko YJ,Lu TC. Analgesic and anti-inflammatory activities of the aqueous extracts from three Flemingia species[J]. Am J Chin Med,2010,38(3):625-638.
[23] Hui-Ya Ho,Ji-Bin.Flemingia macrophylla Extract Ameliortes Experimental Osteoporosis in Ovariectomized Rats[J].Evidence-Based Complementary and Alternative Medicine,2011,2(14),18-27.
[24] Li L,Deng X.A new coumestan with immunosuppressive activities from Flemingia philippinensis[J].Fitoterapia,2011,82(4):615-619.
[25] 王学勇.千斤拔中的天然雌激素[J].国际中医中药杂志,2006,28(3):150.
[26] 韦丽君,陈惠民,王建慧.壮药千斤拔饮对去卵巢大鼠免疫内分泌影响的研究[J].广西中医药, 2009,32(6):46-49.
[27] Hsieh PC,Ho YL.Hepatoprotective effect of the aqueous extract of Flemingia macrophylla on carbon tetrachloride-induced acute hepatotoxicity in rats through ant-oxidative activities[J]. Am J Chin Med, 2011,39(2):349-365.
[28] 周卫华,米长忠,吴仕筠,等.千斤拔醇提物抗小鼠运动疲劳的作用[J].中国老年学杂志, 2013,33(13):3095-3097.
[29] 王娇,范贤,岑颖洲.千斤拔的抗肿瘤活性成分研究[J].天然产物研究与开发, 2013,25(10): 1315-1319,1361.
[30] 袁建新,倪立新,冯凯,等.千斤拔、人参茎叶皂甙对Wistar大鼠坐骨神经损伤保护作用的实验研究[J].中国煤炭工业医学杂志,2002,5(4):405.
[31] 冯凯,林世和,赵节绪,等.千斤拔对大鼠坐骨神经损伤保护作用的实验研究[J].中国中西医结合杂志,1999,19(S1):104-106.
[32] 饶伟文,黄建楷,温志芳,等.千斤拔的品种调查与质量研究[J].中草药, 1999,30(3):219-222.
[33] 祁晓晨,王航,邱晟,等.千斤拔对吗啡依赖离体豚鼠回肠戒断性收缩作用的研究[J].浙江中医药大学学报,2009,33(6):763-765.

相似文献/References:

[1]乔佛晓,禹玉洪,李燕.荜茇的药理作用与毒性作用研究概述[J].环球中医药,2015,8(04):507.[doi:10.3969/j.issn.1674-1749.2015.04.038]
　QIAO Fo-xiao,YU Yu-hong,LI-Yan..Overview of pharmacological action and toxic effects of Piper Longum[J].,2015,8(12):507.[doi:10.3969/j.issn.1674-1749.2015.04.038]
[2]孙爱静 庞素秋 王国权.中药白及化学成分与药理活性研究进展[J].环球中医药,2016,9(04):507.[doi:10.3969/j.issn.1674-1749.2016.04.038]
　SUN Ai-jing,PANG Su-qiu,WANG Guo-quan,et al.Advances of chemical constituents and pharmacological activities of Bletilla striata[J].,2016,9(12):507.[doi:10.3969/j.issn.1674-1749.2016.04.038]
[3]黄弥娜,曹青青,李云青,等.瑞香狼毒毒性部位的化学成分研究[J].环球中医药,2016,9(09):1059.[doi:10.3969/j.issn.1674-1749.2016.09.007]
　HUANG Mi-na,CAO Qing-qing,LI Yun-qing,et al.Study on chemical constituents of toxicity parts in Stellera chamaejasme L.[J].,2016,9(12):1059.[doi:10.3969/j.issn.1674-1749.2016.09.007]
[4]尹泽楠,徐柯心,樊娇娇,等.中国兰科开唇兰属植物化学成分研究进展[J].环球中医药,2016,9(09):1153.[doi:10.3969/j.issn.1674-1749.2016.09.041]
　YIN Ze-nan,XU Ke-xin,FAN Jiao-jiao,et al.Research progress on chemical constituents of Anoectochilus and pharmacological activities[J].,2016,9(12):1153.[doi:10.3969/j.issn.1674-1749.2016.09.041]
[5]何媛媛,王金凤,郭丽娜,等.意大利牛舌草化学成分及药理作用研究进展[J].环球中医药,2017,10(01):114.[doi:10.3969/j.issn.1674-1749.2017.01.039]
　Research progress of chemical components and pharmacologic effects of Anchusa italica Retz..Research progress of chemical components and pharmacologic effects of Anchusa italica Retz.[J].,2017,10(12):114.[doi:10.3969/j.issn.1674-1749.2017.01.039]
[6]夏青 徐柯心 张文婷 王雨彤 黄碗贞 罗隽 樊娇娇 王宝丽 马志强 林瑞超.中药狼毒化学成分与药理作用概述[J].环球中医药,2017,10(08):927.[doi:10.3969/j.issn.1674-1749.2017.08.039]
　XIA Qing,XU Kexin,ZHANG Wenting,et al.Overview on chemical compounds and pharmacological effects of radix euphorbiae lantu[J].,2017,10(12):927.[doi:10.3969/j.issn.1674-1749.2017.08.039]
[7]邢峰丽,封若雨,孙芳,等.皂角刺的药理作用研究进展[J].环球中医药,2017,10(10):1167.[doi:10.3969/j.issn.1674-1749.2017.10.035]
　XING Fengli,FENG Ruoyu,SUN Fang,et al.Research progress on pharmacological action of Chinese honeylocust spine[J].,2017,10(12):1167.[doi:10.3969/j.issn.1674-1749.2017.10.035]

备注/Memo

备注/Memo:
-
更新日期/Last Update: 1900-01-01