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[1]刘绍永,傅延龄.大承气汤临床观察类文献方药用量分析[J].环球中医药,2016,9(05):571-574.[doi:10.3969/j.issn.1674-1749.2016.05.012]
　LIU Shao-yong,FU Yan-ling..Analysis of herbal dosages of the literature on the clinical observation of Dachengqi decoction[J].,2016,9(05):571-574.[doi:10.3969/j.issn.1674-1749.2016.05.012]
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大承气汤临床观察类文献方药用量分析()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第9卷
期数:
2016年05期
页码:
571-574
栏目:
文献研究
出版日期:
2016-05-06

文章信息/Info

Title:
Analysis of herbal dosages of the literature on the clinical observation of Dachengqi decoction
作者:
刘绍永; 傅延龄
100029 北京中医药大学基础医学院[刘绍永(硕士研究生)],继续教育学院(傅延龄)
Author(s):
LIU Shao-yong;  FU Yan-ling.
School of Basic Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
关键词:
大承气汤;  临床观察;  剂量
Keywords:
Dachengqi decoction;  Clinical observation;  Dosage
分类号:
R289
DOI:
10.3969/j.issn.1674-1749.2016.05.012
文献标志码:
A
摘要:
为了了解当代医家对于大承气汤方的剂量应用情况,本研究尝试通过对当代医家发表的相关临床观察类文献进行搜集和整理,并对包含大承气汤方中4味药物的处方进行分析,发现纳入文献的单味药用量分布区间大于《中华人民共和国药典》(一部)(简称:《药典》)的用量范围,各单味药的最大用量均在《药典》最大量的2倍以上; 与仲景方相比,纳入文献的单味药量明显偏小,仲景方中四味药物的最小用量均在纳入文献的4倍以上,从药物用量两两比较的结果来看,频次最高的比值均为1.00,表明临床中对于方药的配伍比例不够重视。从加味药物的出现频次来看,排在前10位的大多是行气活血类药,并且排在前三位的桃仁、赤芍、莱菔子与经方中四药相合正是复方大承气汤的组成。从涉及的疾病种类及其频次来看,肠梗阻与急性胰腺炎位居前二,四位药物在两种不同病种之间的用量十分接近。
Abstract:
In order to understand the dosage application of Dachengqi decoction formula which was used by contemporary doctors, the relevant literatures of clinical observation of Dachengqi decoction published by contemporary doctors were collected and classified in this study, and analyzed the four herbs of Dachengqi decoction. The results indicated that compared with dosage rangerecorded in Chinese pharmacopoeia, dosage distribution interval of each single herb in these selected literatures was larger, and the maximum dosage of each herb was even two times than that in the Chinese pharmacopoeia; In comparison with the dosage recorded by Zhang Zhong-jing, dosage of each single herb of these selected literatures was much lower, and the minimum dosages of these four herbs from Zhongjing's formulae were 4 times more than those in these selected literatures; From perspective of pairwise comparison of herbal dosages of these four herbs, the specific value of the most commonly seen frequency was 1.00, the results showed that the proportion of the compatibility of prescription in clinic was not paid enough attention. With regard to frequency of modified herbs,, the first 10 were herbs with actions of moving qi and activating blood, and the top 3 herbs were Taoren, Chishao, and Laifuzi, which were composition of Dachengqi decoction; With regard to the variety and frequency of disease, intestinal obstruction and acute pancreatitis were in the first two places, and the dosages of the four herbs in treatment of these two different diseases were quite close.

参考文献/References:

[1] 闫韶花,陈欣燕,焦拥政,等.大承气汤治疗肠梗阻临床用量研究[J].中医杂志,2013,54(22):1953-1956.
[2] 高学敏.中药学[M].北京:中国中医药出版社,2007:253.
[3] 赵思佳,傅延龄,张林.葛根芩连汤临床观察类文献方药用量分析[J].中国临床医生,2014,42(2):79-82.
[4] 傅延龄,宋佳,张林.论张仲景对方药的计量只能用东汉官制[J].北京中医药大学学报,2013,36(6):365-369.
[5] 范吉平,程先宽.经方剂量揭秘[M].北京:中国中医药出版社,2009:3.
[6] 国家药典委员会.中华人民共和国药典(2010版)[S].北京:中国医药科技出版社,2010:22,118,230,235.
[7] 彭小兰.中西医结合治疗急性有机磷农药中毒60例临床观察[J].中医药导报,2007,13(5):61-62.
[8] 宋佳.经方50味药物在明代13位医家中的用量规律研究[D].北京:北京中医药大学,2010:148.
[9] 吴咸中.中西医结合急腹症方药诠释[M].天津:天津科学技术出版社,2001:360-361.

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备注/Memo

备注/Memo:
作者简介: 刘绍永(1986- ),2013级在读硕士研究生。研究方向:伤寒论和方药量效关系。E-mail:shaoyong456@163.com
通讯作者: 傅延龄(1959- ),博士,教授,博士生导师。研究方向:伤寒论和方药量效关系。E-mail:fuyanling@bucm.edu.cn
更新日期/Last Update: 2016-05-06