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[1]李瑞根,王威,徐日,等.针刺治疗肠易激综合征Meta分析[J].环球中医药,2016,9(06):772-776.[doi:10.3969/j.issn.1674-1749.2016.06.044]
　LI Rui-gen,Wang Wei,XU Ri,et al.Meta analysis of acupuncture in treatment of irritable bowel syndrome[J].,2016,9(06):772-776.[doi:10.3969/j.issn.1674-1749.2016.06.044]
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针刺治疗肠易激综合征Meta分析()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第9卷
期数:
2016年06期
页码:
772-776
栏目:
综述
出版日期:
2016-06-06

文章信息/Info

Title:
Meta analysis of acupuncture in treatment of irritable bowel syndrome
作者:
李瑞根; 王威; 徐日; 李博; 徐晓蓓; 卜维静
110032 沈阳,辽宁中医药大学针灸推拿学院
Author(s):
LI Rui-gen;  Wang Wei;  XU Ri; et al.
College of Acu-moxibustion and Tuina,Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China
关键词:
针刺疗法;  肠易激综合征;  Meta分析
Keywords:
Acupuncture therapy;  Irritable bowel syndrome;  Meta-analysis
分类号:
R245.3
DOI:
10.3969/j.issn.1674-1749.2016.06.044
文献标志码:
A
摘要:
目的 评价针刺治疗肠易激综合征(irritable bowel syndrome,IBS)的疗效和安全性。方法 计算机检索Cochrane、PubMed、EMBASE、CBM、CNKI、万方、VIP等数据库,配合手工检索以提高查全率; 使用“偏倚风险评估工具”评价文献的方法学质量,Review Manager 5.3进行Meta分析。结果 纳入合格研究12篇,总计715病例数,Meta分析示随访3个月复发率:95%CI为[0.35～0.68],P<0.00001,提示试验组(针刺)随访3个月复发率小于对照组; 针刺或针刺+西药vs西药临床症状改善总体有效率:95%CI为[1.08～1.26],P<0.0001,并且漏斗图结果显示基本对称,提示试验组改善IBS临床症状优于对照组。结论 受纳入研究方法学质量不高及偏倚风险客观存在,本研究所提供证据尚不足以证明针刺治疗肠易激综合征疗效优于对照组。亟待今后的临床试验能用高质量、多中心大样本随机对照试验进一步验证针刺治疗肠易激综合征的疗效。
Abstract:
Objective To evaluate the efficacy and safety of acupuncture in the treatment of irritable bowel syndrome. Methods All the information came from Cochrane, PubMed, EMBASE, CBM, CNKI, Wanfang, VIP database, and manual searching was used to improve the recall ratio. The risk of bias(ROB)tool was used to evaluate the quality of literature methodology, the Review Manager 5.3 was used for the Meta-analysis. Results 12 eligible trials(n=715)were included, Meta analysis showed that the recurrence rate of 3 months: 95%CI [0.35～0.68], P<0.00001, 3 months follow-up recurrence rate of the treatment group(acupuncture)was lower than that of control group, Acupuncture or acupuncture plus Western medicine compared with Western medicine, the overall response rates of clinical symptoms improvemen: 95%CI [1.08～1.26] P<0.00001, and funnel plot results showed the atlas were basic symmetry, suggesting that the clinical symptoms of IBS of experimental group was better than that of the control group. Conclusions Due to the poor assessment of methodological quality of all the inclusive studies and the risk of bias exists objectively. The evidenceof this systematic review wasn't sufficient to prove that the effect of acupuncture was better than the control group. Hoping the future clinical trials with high quality, multi centerand large samples randomized controlled trials to further verify the clinical curative effect of acupuncture for IBS.

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备注/Memo

备注/Memo:
基金来源: 辽宁省科技厅优秀人才培育计划(2015020374)
作者简介: 李瑞根(1989- ),2013级在读硕士研究生。研究方向:针刺临床机理研究。E-mail:begeer1314@163.com
通讯作者: 王威(1965- ),女,博士,教授。研究方向:针刺临床机理研究。E-mail:syweil@163.com
更新日期/Last Update: 2016-06-06