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[1]王志斌 李军祥 余轶群 陈建新.基于因子分析及复杂系统熵聚堆法的酒精依赖症中医证候研究[J].环球中医药,2016,9(10):1161-1165.[doi:10.3969/j.issn.1674-1749.2016.10.001]
　WANG Zhi-bin,LI Jun-xiang,YU Yi-qun,et al.Study of TCM syndrome characteristics of ADS based on factor analysis and complex system entropy cluster[J].,2016,9(10):1161-1165.[doi:10.3969/j.issn.1674-1749.2016.10.001]
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基于因子分析及复杂系统熵聚堆法的酒精依赖症中医证候研究()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第9卷
期数:
2016年10期
页码:
1161-1165
栏目:
论著
出版日期:
2016-10-06

文章信息/Info

Title:
Study of TCM syndrome characteristics of ADS based on factor analysis and complex system entropy cluster
作者:
王志斌 李军祥 余轶群 陈建新
100078 北京中医药大学东方医院消化科(王志斌、李军祥、余轶群); 北京中医药大学信息中心(陈建新)
Author(s):
WANG Zhi-bin; LI Jun-xiang; YU Yi-qun; et al.
Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078,China
关键词:
酒精依赖症;  证候;  因子分析;  熵聚堆
Keywords:
Alcohol dependence syndrome;  TCM syndrome;  Factor analysis;  Complex system entropy cluster
分类号:
R2-03
DOI:
10.3969/j.issn.1674-1749.2016.10.001
文献标志码:
A
摘要:
目的 探讨酒精依赖症(alcohol dependence syndrome,ADS)的中医临床证候分类,为临床证候规范化研究奠定基础。方法 本研究观察211例符合酒精依赖症诊断的门诊及住院患者,利用中医证候量表收集患者的中医证候学信息,将上述信息数字化后,通过因子分析法及复杂系统熵聚堆法分析中医证候分布特点。结果 酒精依赖症中医临床证候主要包含通过因子分析和复杂系统熵聚堆对酒精依赖症的中医证候分类分析后,得出以下6个证型:肝肾阴虚,湿热气滞证(37例,17.5%); 肝阳上亢,阴虚内热证(19例,9.0%); 脾虚肝郁,湿热瘀阻证(66例,31.3%); 脾虚湿困证(18例,8.5%); 肝郁气滞,阴虚血瘀证(49例,23.2%); 湿热内盛证(22例,10.4%)等6个证型。结论 ADS的主要病位在肝、脾两脏,随着疾病的发展可波及肾,关键的病理因素是湿热,关键病机是饮酒无度、脾胃受损、脾虚不运、湿浊困脾。
Abstract:
Objective To explore the classification of TCM clinical syndromes of alcohol dependence syndrome(ADS), and lay the foundation for the standardization of clinical syndromes. Methods 211 patients with ADS were recruited in the study. The data were collected to assessment of TCM syndrome and the data of liver function were collected and analyzed by factor analysis and complex system entropy cluster. Results ADS included 6 TCM syndrome types which was liver-kidney yin deficiency, dampness-heat and qi stagnation(37 cases, 17.5%); hyperactivity of liver-yang, yin deficiency with internal heat(19 cases, 9.0%); spleen deficiency and liver depression, dampness-heat and blood stasis(obstruction)(66 cases, 31.3%); spleen deficiency with dampness accumulation(18 cases, 8.5%); liver depression and qi stagnation, yin deficiency and blood stasis(49 cases, 23.2%); and internal dampness-heat(22 cases, 10.4%). Conclusion The main damage to the ADS is liver and spleen, with the development of the disease can affect the kidney, the key of pathological factors of is dampness-heat, the key pathogenesis is alcohol misuse to damage of spleen and stomach, the results is spleen deficiency does not transport and dampness and turbidity trapped spleen.

参考文献/References:

[1] World Health Organization. Global status report on alcohol and health[R]. Geneva:WHO,2011.
[2] 苏中华,郝伟,谌红献.中国五地区饮酒情况及相关问题调查Ⅰ普通人群的饮酒状况[J].中国心理卫生杂志,2003,17(8):536-539.
[3] 贾静源. 北京市海淀区居民饮酒行为流行病学调查[J]. 中国实用医药,2009,4(7):256-257.
[4] 中华中医药学会. 中医内科常见病诊疗指南:中医病证部分[M].北京:中国中医药出版社,2008:144-147.
[5] 徐迪华,徐剑秋. 中医量化诊断[M].南京:江苏科学技术出版社,1997:21-138.
[6] 郭蕾,王永炎,张志斌.关于证候概念的诠释[J].北京中医药大学学报,2003,26(2):5-8.
[7] 林威君.台湾高雄地区非酒精性脂肪性肝病的临床研究[D].北京:北京中医药大学,2010:53-56.
[8] 王天芳,吴秀艳,陈建新,等. 基于信息熵关联度系数法的证候/证候要素提取研究[J].天津中医药,2009,26(4):274-276.
[9] 陈静,西广成,易建强,等. 中医复杂系统中两类分划方法的比较[J].烟台大学学报:自然科学与工程版,2006,19(专集):430-434.
[10] 李丰衣,孙劲晖,田德禄.田德禄教授治疗酒精性肝纤维化经验浅探[J].吉林中医药,2006,26(8):10-11.
[11] 王睿林,李捍卫,金波,等. 从中医体质角度认知酒精性肝病[J].安徽中医学院学报,2011,30(2):3-5.

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备注/Memo

备注/Memo:
基金项目: 国家中医重点专科建设项目(ZJ0101PW008); 北京中医药大学自主选题(2011JYB22JS-036)
作者简介:王志斌(1978- ),硕士,副主任医师。研究方向:应用中医药治疗消化系统疾病。E-mail:wangsanger@126.com
更新日期/Last Update: 2016-10-06