|本期目录/Table of Contents|

[1]曲圣元 陈荷清 车蕊 张明 刘柳青 马文珠.火针和毫针干预对佐剂性关节炎模型大鼠的比较研究[J].环球中医药,2016,9(11):1305-1309.[doi:10.3969/j.issn.1674-1749.2016.11.006]
　QU Sheng-yuan,CHEN He-qing,CHE Rui,et al.Comparative study of fire needle and filiform needle on adjuvant arthritis model rats[J].,2016,9(11):1305-1309.[doi:10.3969/j.issn.1674-1749.2016.11.006]
点击复制

火针和毫针干预对佐剂性关节炎模型大鼠的比较研究()
     
分享到：

《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第9卷
期数:
2016年11期
页码:
1305-1309
栏目:
论著
出版日期:
2016-11-06

文章信息/Info

Title:
Comparative study of fire needle and filiform needle on adjuvant arthritis model rats
作者:
曲圣元 陈荷清 车蕊 张明 刘柳青 马文珠
100029 北京中医药大学针灸推拿学院[曲圣元(本科生)、陈荷清、车蕊、张明、刘柳青、马文珠]
Author(s):
QU Sheng-yuan; CHEN He-qing; CHE Rui; et al.
Institute of acupuncture and tuina, Beijing University of Chinese Medicine,Beijing 100029,China
关键词:
针灸;  火针;  佐剂性关节炎模型
Keywords:
Acupuncture;  Fire needle;  Adjuvant arthritis model
分类号:
R245.3
DOI:
10.3969/j.issn.1674-1749.2016.11.006
文献标志码:
A
摘要:
目的 探究火针和毫针干预对于佐剂性关节炎模型大鼠的影响。方法 实验以佐剂性关节炎(AA)模型大鼠作为研究对象,将雄性Wistar大鼠适应性饲养1周后,随机分为空白对照组、火针组、毫针组、模型对照组,每组10只。每隔3天测量各组大鼠踝部肿胀情况、体质量变化并进行疼痛测量评定。在造模后第28天每组随机处死2只大鼠,观察左侧踝关节组织切片和足三里部位组织切片。结果 40只大鼠均进入结果分析。火针组、毫针组大鼠经针刺后左踝直径与模型对照组比较有显著性降低(P<0.05),关节疼痛评分与模型对照组比较也有显著性降低(P<0.05)。踝关节切片也可见局部组织炎性反应得到改善,观察足三里部位组织切片可见火针针刺可对肌肉组织造成损伤,但愈合较好。结论 火针和毫针干预对于佐剂性关节炎大鼠的症状改善有一定作用,两种针刺方式对肌肉组织损伤较小且愈合良好。
Abstract:
Objective To explore and compare the influence of fire needle and filiform needle on adjuvant arthritis model rats. Methods Adjuvant arthritis(AA)model rats were used for this study. After the male Wistar rats were allowed to acclimate for 1 week,the rats were randomly divided into normal group,AA model group,acupuncture needle group,fire needle group,10 rats in each group. The swelling rate of ankle,weight,joint pain score of each group were measured every 3 days. 28 days after the molding,2 rats were sacrificed in each group randomly, the tissue section of the left ankle joint and “Zusanli” were observed. Results Totally 40 rates were involved in the result analysis. Compared with the model group, the left ankle diameter and joint pain score of the filiform needle and fire needle group were decreased significantly(P<0.05). Pathology of the joint indicated that acupuncture has the effect of relieving the inflammation; pathology of “Zusanli” showed that fire needle may damage the muscle,but well healed. Conclusion Fire needle and filiform needle has a certain effects on improving the symptoms of adjuvant arthritis model rats, the two methods have small damage to the muscle and good healing..

参考文献/References:

[1] Huang C,Hu Z P,Long H,et al.Attenuation of mechanical but not thermal hyperalgesia by electroacupuncture with the involvement of opioids in rat model of chronic inflammatory pain[J].Brain Research Bulletin,2004,63(2):99-103.
[2] 张传英,邵芙蓉,蔡荣林,等.艾灸对类风湿性关节炎大鼠关节滑膜组织转录信号转导因子1、细胞因子信号负调控因子基因表达的影响[J].针刺研究,2015,40(3):205-209.
[3] 张露芬.实验针灸学[M].北京:化学工业出版社,2010:221-222.
[4] 黄怡然.单穴和双穴电针对慢性佐剂性关节炎模型大鼠相关细胞因子影响的研究[D].北京:北京中医药大学,2010.
[5] 杨介宾,宋开源,梁繁荣,等.针灸疗法对佐剂性关节炎大鼠外周镇痛机理的研究[J].中国针灸,1999,6:364.
[6] 申伟,汤继芹,张永臣.申脉穴古代主治病证及刺灸特点分析[J].四川中医,2015,33(3):21-22.
[7] 施茵,吴焕淦.足三里穴在免疫功能调节中的应用[J].现代中医药,2003,(3):3-5.
[8] 明·杨继洲.针灸大成[M].靳贤,补辑重编.黄龙祥,整理.北京:人民卫生出版社,2006:328-332.
[9] 唐成林.“缪刺法”对佐剂性关节炎大鼠的镇痛效应及机制研究[D].重庆:重庆医科大学,2008
[10] 李辉,李晓泓,张露芬,等.电针“大椎”“命门”对佐剂性关节炎大鼠应激相关因子影响的实验研究[J].针刺研究,2006,31(1):8-11.
[11] 孙云廷.针灸治疗类风湿性关节炎动物实验研究进展[J].光明中医,2007,22(2):51-53.

相似文献/References:

[1]李兆鑫 李倩倩 刘丽英等.针刺调节心率变异性作用机制的研究进展[J].环球中医药,2014,7(02):143.
　LI Zhao xin,LI Qian qian,LIU Li ying,et al.Rearch progress on the mechanism of acupuncture for heart rate variability[J].,2014,7(11):143.
[2]江丹.中医针灸治疗手术后并发症验案4则[J].环球中医药,2013,6(02):134.
[3]王伟明,许焕芳,刘志顺,等.针灸治疗原发性卵巢功能不全的文献回顾[J].环球中医药,2013,6(03):213.
　WANG Wei ming,XU Huan fang,LIU Zhi shun..Literature review of acupuncture and moxibustion for treatment of primary ovarian insufficiency[J].,2013,6(11):213.
[4]刘锋,李响.针灸治疗持续性植物状态的研究进展[J].环球中医药,2013,6(08):632.
　LIU Feng,LI Xiang..Research progress on acupuncture and moxibustion for treatment of persistent vegetative state[J].,2013,6(11):632.
[5]王冬琴,赵琛,崔云华,等.针灸延缓衰老的机制研究进展[J].环球中医药,2012,5(01):75.
　WANG Dong qin,ZHAO Chen,CUI Yun hua,et al.Research progress on the mechanism of acupuncturemoxibustion for antiaging[J].,2012,5(11):75.
[6]林玉芳,沈红强,王义军,等.针灸治疗类风湿性关节炎取穴方法的文献回顾[J].环球中医药,2012,5(11):866.
　LIN Yu fang,SHEN Hong qiang,WANG Yi jun..Preliminary discuss the methods of acupoints selection in acupuncture and moxibustion treatment of RA[J].,2012,5(11):866.
[7]苏伟潮 张宏.《医经小学》针灸学术思想探微[J].环球中医药,2014,7(08):615.
[8]王磊 曹丽翠 金莲.黄银兰教授火针治验举隅[J].环球中医药,2014,7(08):646.
[9]包飞 孙华 王道海.西医本科生《针灸治疗学》教学体会[J].环球中医药,2014,7(10):785.
[10]沈惠军 Man-Chi Wong.海外对针灸作用原理研究的概述[J].环球中医药,2014,7(12):966.
　SHEN Hui-jun,Man-Chi Wong.An Overview of the Overseas Studies on the Mechanism of Acupuncture[J].,2014,7(11):966.

备注/Memo

备注/Memo:
基金项目: 2015国家级创新训练项目(201510026033)
作者简介: 曲圣元(1994- ),女,2012级在读本科生。研究方向:影响针灸效应相关参数的研究。E-mail:497984361@qq.com
通讯作者: 马文珠(1960- ),女,硕士,教授。研究方向:影响针灸效应相关参数的研究。E-mail:mawenzhu@139.com
更新日期/Last Update: 2016-11-06