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[1]王至骏 王晓素 陈宇华 孔婧 吕秀华.人参、党参、太子参对SD雌性大鼠性成熟的影响[J].环球中医药,2017,10(05):544-547.[doi:10.3969/j.issn.1674-1749.2017.05.008]
　WANG Zhijun,WANG Xiaosu,CHEN Yuhua,et al.Effect of ginseng, radix codonopsis, radix pseudostellariae on sexual maturation of female SD rats[J].,2017,10(05):544-547.[doi:10.3969/j.issn.1674-1749.2017.05.008]
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人参、党参、太子参对SD雌性大鼠性成熟的影响()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第10卷
期数:
2017年05期
页码:
544-547
栏目:
论著
出版日期:
2017-05-06

文章信息/Info

Title:
Effect of ginseng, radix codonopsis, radix pseudostellariae on sexual maturation of female SD rats
作者:
王至骏 王晓素 陈宇华 孔婧 吕秀华
201203 上海,华东师范大学附属第二中学生物学教研室[王至骏(高中生)、吕秀华]; 上海中医药大学附属岳阳中西医结合医院消化科[王晓素、孔婧、陈宇华(硕士研究生)]
Author(s):
WANG Zhijun; WANG Xiaosu; CHEN Yuhua; et al.
Department of biology, The Second Affiliated Middle School of East China Normal University, Shanghai 201203,China
关键词:
人参;  党参;  太子参;  性早熟
Keywords:
Ginseng;  Radix codonopsis;  Radix pseudostellariae;  Precocious puberty
分类号:
R285
DOI:
10.3969/j.issn.1674-1749.2017.05.008
文献标志码:
A
摘要:
目的 观察人参、党参、太子参对SD雌性大鼠生长发育的影响。 方法 将动物随机分为对照组、人参组、党参组及太子参组,分别予生理盐水、人参、党参和太子参灌胃2周,并每天行阴道涂片检查,干预前后检测雌二醇(Estrogen,E2)水平,最后解剖大鼠,取出卵巢和子宫,计算卵巢指数和子宫指数。结果 四组大鼠比较,性成熟时间和卵巢指数未见明显差异; 与对照组相比,党参组、人参组的E2水平明显升高(P＜0.05); 与对照组和太子参组相比,人参组的子宫指数较大(P＜0.05); 与对照组相比,三个给药组大鼠体重增长较多(P＜0.05)。结论 党参和人参在一定程度上可能导致SD雌性大鼠的性早熟; 人参、党参、太子参能促进SD雌性大鼠体重的增长。
Abstract:
Objective To observe the effects of ginseng, radix codonopsis and radix pseudostellariae on the growth and development of SD female rats. Methods Animals were randomly divided into four groups: control group, ginseng group, radix codonopsis group and radix pseudostellariae group, intragastric administration for 2 weeks with normal saline, ginseng, radix codonopsis and radix pseudostellariae, vaginal smears were taken every day. The levels of estrogen before and after intervention were detected. The ovarian index and uterine index was calculated. Results There was no significant difference in sexual maturation time and ovarian index of the four groups. Compared with the control group, the E2 level of radix codonopsis group and ginseng group was significantly increased(P＜0.05). Compared with the control group and the radix pseudostellariae group, the uterus index of the ginseng group was larger(P＜0.05). Compared with the control group, the rats in the rest groups had more weight gain(P＜0.05). Conclusion Ginseng and radix codonopsis may lead to precocious puberty of SD female rats in a certain degree; Ginseng,radix codonopsis and radix pseudostellariae can promote the weight growth of SD female rats.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目: 上海市中西医结合学会科研基金(ZXYK-1213)
作者简介: 王至骏(1999- ),高中三年级在读。E-mail:wmz111wmz222@126.com
通信作者: 王晓素(1967- ),女,博士,主任医师,博士生导师,中华中医药学会脾胃病分会委员。研究方向:中西医结合防治消化系统疾病。E-mail:xswangxs0084@163.com
更新日期/Last Update: 2017-05-06