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[1]曹爱玲 何海浪 周贤梅.针刺治疗慢性阻塞性肺疾病疗效的Meta分析[J].环球中医药,2017,10(07):799-804.[doi:10.3969/j.issn.1674-1749.2017.07.038]
　CAO Ailing,HE Hailang,ZHOU Xianmei..Meta analysis of the therapeutic effect of acupuncture on chronic obstructive pulmonary disease[J].,2017,10(07):799-804.[doi:10.3969/j.issn.1674-1749.2017.07.038]
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针刺治疗慢性阻塞性肺疾病疗效的Meta分析()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第10卷
期数:
2017年07期
页码:
799-804
栏目:
综述
出版日期:
2017-07-06

文章信息/Info

Title:
Meta analysis of the therapeutic effect of acupuncture on chronic obstructive pulmonary disease
作者:
曹爱玲 何海浪 周贤梅
210009 南京中医药大学附属医院呼吸科[曹爱玲(硕士研究生)、何海浪、周贤梅]
Author(s):
CAO Ailing;  HE Hailang; ZHOU Xianmei.
The Affiliated Hospital of Nanjing University of Chinese Medicine,210009 Jiangsu,China
关键词:
针刺;  慢性阻塞性肺疾病;  Meta分析
Keywords:
Acupuncture;  Chronic obstructive pulmonary diseases;  Meta-analysis
分类号:
R563.1
DOI:
10.3969/j.issn.1674-1749.2017.07.038
文献标志码:
A
摘要:
目的 系统评价针刺治疗慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)的疗效。方法 计算机检索Pubmed、Cochrane library、EMBASE、中国知网、万方数据库、维普、中国生物医学文献数据库等数据库,检索针刺治疗COPD的随机安慰对照试验。检索时限为各库建库时间至2016年7月,任何语言的文献都在检索范围之内。由两名评价者提取数据、独立评价并交叉核对纳入文献质量,采用Review Manager 5.2对符合条件的文献进行Meta分析。结果 共纳入9篇临床随机对照试验(RCTs),其中包括5篇英文文献和4篇中文文献,共计326名患者。Meta分析提示:针刺能明显提高患者的第一秒钟用力呼气容积占预计值百分比(forced expiratory volume in one second,FEV1%)[Z=3.16, 95%CI(1.87,7.99), P=0.002]及第一秒钟用力呼气容积占用力肺活量百分比(FEV1/forced vital capacity,FVC%)[Z=2.05, 95%CI(0.34,14.80),P=0.04],同时能降低患者的圣乔治呼吸问卷评分(SGRQ)[Z=3.24,95%CI(-14.44,-3.56),P=0.001],增加患者的六分钟步行距离(6-minute walk distance,6-MWD)[Z=2.37,95%CI(5.85,61.52),P=0.02]。结论 针刺治疗可增加COPD患者的肺通气功能,提高其运动耐量,并改善生活质量,但仍需要大样本的高质量随机对照试验进一步证实。
Abstract:
Objective To evaluate the effect of acupuncture on chronic obstructive pulmonary diseases. Methods The randomized controlled trials of acupuncture in treatment of chronic obstructive pulmanory disease(COPD)in the Pubmed, Cochrane database, EMBASE, CNKI, Wanfang Standards Database, VIP database,CBM were selected systematically from their inception to February 2016. Any language of literature was included. The selection of the studies, data abstraction, methodological quality was performed independently and cross-checked by two researchers. The Review Manager 5.2 software was used for Meta-analysis. Results 16 articles with 326 patients were included, five English literature and four Chinese literature were included in this study. Meta-analysis indicated that Acupuncture could significantly improve FEV1% [Z=3.16, 95%CI(1.87, 7.99), P=0.002] and FEV1/FVC% [Z=2.05, 95%CI(0.34, 14.80), P=0.04]. Acupuncture also could significantly lower ST.George's score(SGRQ)[Z=3.24, 95%CI(-14.44, -3.56), P=0.001] and could increase six-minute walk distance(6MWD)[Z=3.19, 95% CI(5.85, 61.52), P=0.02]. Conclusion Acupuncture treatment can increase pulmonary ventilation function and improve exercise tolerance and quality of life in COPD patients. However, a large sample of high-quality randomized controlled trials are needed to further confirm.

参考文献/References:

[1] World Health Organization.Chronic Obstructive Pulmonary Disease[EB/OL].(2015-01-02)
[2016-02-02]. http://www.who.int/ respiratory/ copd/en/.
[2] Mathers CD, Loncar D.Projections of global mortality and burden of disease from 2002 to 2030[J].PLoS Med,2006,3(11):442.
[3] 张新芳,赵蜀军,蔡圣荣,等.电针足三里对慢性阻塞性肺疾病大鼠肺功能及白细胞介素-1β和白细胞介素-6的影响[J].安徽中医学院学报,2013,32(4):44-47.
[4] 程淼,张新芳,张洁,等.针刺治疗对COPD模型大鼠TH1/TH2细胞亚群格局的影响[J].中国老年学杂志,2014,34(2):399-402.
[5] 刘鸣.系统评价、Meta分析设计与实施方法[M].北京:人民卫生出版社,2011:68-71.
[6] Liu X,Fan T,Lan Y,et al.Effects of Transcutaneous Electrical Acupoint Stimulation on Patients with Stable Chronic Obstructive Pulmonary Disease: A Prospective, Single-Blind, Randomized, Placebo-Controlled Study[J].J Altern Complement Med,2015,21(10):610-616.
[7] 童娟,郭泳梅,何颖,等.针刺对稳定期慢性阻塞性肺病患者运动耐量的调节作用:随机对照研究[J].中国针灸,2014,34(9):846-850.
[8] 郭泳梅,童娟,姚红.针刺疗法对稳定期慢性阻塞性肺疾病患者呼吸功能的影[J].广州中医药大学学报,2013,30(5):658-663.
[9] Suzuki M, Muro S, Ando Y,et al.A randomized, placebo-controlled trial of acupuncture in patients with chronic obstructive pulmonary disease(COPD): the COPD-Acupuncture trial(CAT)[J].Archives of internal medicine,2012,172(11):878-886.
[10] 文谦,李宁,喻鹏铭.定喘穴经皮神经电刺激对COPD急性期患者肺功能的影响:随机对照研究[J].中国针灸,2011,31(2):97-100.
[11] Ngai S P C,Jones A Y M,Hui-Chan C W Y,et al.Acute effects of Acu-TENS on FEV1 and blood β-endorphin level in chronic obstructive pulmonary disease[J].Altern Ther,2011,17(5):8-13.
[12] Ngai S P C,Jones A Y M,Hui-Chan C W Y, et al. Effect of 4 weeks of Acu-TENS on functional capacity and β-endorphin level in subjects with chronic obstructive pulmonary disease: a randomized controlled trial[J].Respiratory physiology & neurobiology,2010,173(1):29-36.
[13] 邵媚媚,曹琳,刘智艳.针刺联合穴位贴敷治疗慢性阻塞性肺疾病急性发作期15例[J].中医杂志,2012,53(7):606-607.
[14] Jobst K,Mcpherson K,Brown V,et al.Controlled trial of acupuncture for disabling breathlessness[J].The Lancet,1986,2(8521):1416-1419.
[15] Huang E T Y,Di PhD Y M.Acupuncture Therapies for Chronic Obstructive Pulmonary Disease: A Systematic Review of Randomized, Controlled Trials[J].Alternative therapies in health and medicine,2014,20(6):10-23.
[16] Choi T Y,Jun J H, Choi J Y, et al.Acupuncture for the treatment of chronic obstructive pulmonary disease: a protocol of a systematic review[J].BMJ open,2014,4(4):297-301.
[17] Musial F, Lund I, Näslund J, et al. Minimal acupuncture is not a valid placebo control in randomised controlled trials of acupuncture: a physiologist's perspective[J].Chinese Medicine,2009,4(1):55-56.
[18] Thomas L,Irene L,Audrey S,et al.Is Placebo Acupuncture What It Is Intended to Be?[J].Evidence-Based Complementary and Alternative Medicine,2011,2011(1):1-5.

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备注/Memo

备注/Memo:
基金项目: 江苏省“十二·五”中医药重点学科建设项目(js1302)
作者简介: 曹爱玲(1991- ),女,2015级在读硕士研究生。研究方向:肺脏病临床研究。E-mail:958496371@qq.com
通信作者: 周贤梅(1964- ),女,博士,主任医师,教授,博士生导师。研究方向:中西医结合治疗呼吸系统疾病。E-mail:zhouxianmeijs@aliyun.com
更新日期/Last Update: 2017-07-06