|本期目录/Table of Contents|

[1]姬航宇,仝小林,韩佳瑞,等.《神农本草经》“三品分类”思想对临床合理用量的启示[J].环球中医药,2012,5(06):413-0.
　JI Hang yu,TONG Xiao lin,HAN Jia rui,et al.Threetypedrugs in Shennong Materia Medica and clinical rational dosage[J].,2012,5(06):413-0.
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《神农本草经》“三品分类”思想对临床合理用量的启示()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第5卷
期数:
2012年06期
页码:
413-0
栏目:
中药量效关系研究
出版日期:
2012-06-06

文章信息/Info

Title:
Threetypedrugs in Shennong Materia Medica and clinical rational dosage
作者:
姬航宇; 仝小林; 韩佳瑞; 陈欣燕; 赵林华; 焦拥政;
Author(s):
JI Hangyu; TONG Xiaolin; HAN Jiarui; et al.
Guang′anmen Hospital，Beijing 100053，China
关键词:
神农本草经;  三品分类法;  合理用量
Keywords:
Shennong Materia Medica; Threegrade classification; Rational dosage
分类号:
R28
DOI:
-
文献标志码:
A
摘要:
《神农本草经》(简称《本经》)按药性、药效、毒性等将药物分成上、中、下三品,其中上品药可"多服、久服",中品药的使用应"斟酌其宜",而下品药"多毒,不可久服"。与《中华人民共和国药典》为参照,标识《本经》药物的剂量和毒性,采用描述性统计的方法 ,计算并比较《本经》三品药物的的最大、最小剂量及剂量阈值; 将其与《卫生部关于进一步规范保健食品原料管理的通知》进行对照; 分析三品药物各自的剂量分布特点。结果显示,《本经》的药物三品分类原则为临床合理用量提供了一种思路:上品药物的用量范围可以较为宽泛,中品次之,下品药物用量范围应该最窄。
Abstract:
In Shennong Materia Medica, drugs were divided into three types according to their efficacy, resistance and toxicity. Drugs in first type could be used in a long time, and threshold of dose could be wide. In second type, drugs could be used carefully. Drugs in third type include some poisonous medicine, so the dose should not be high. In the study, the dosage and toxicity of all drugs in Shennong Materia Medica was added according to pharmacopoeis. Maximum, minimum and threshold of dose were calculated. Dosages of drugs in three different types were compared. All drugs in Shennong Materia Medica were compared with the ministry of health on further regulating the raw materials of health food management notice, and analyzed characteristics of dose in three types. It pointed that threegrade classification in Shennong Materia Medica provided a new thought for the clinical rational dosage. The threshold of dose was not same in different type of drugs. Some threshold of dose could be wide than the regulation of pharmacopoeis.

参考文献/References:

[1]马继兴.神农本草经辑注[M].北京:人民卫生出版社,1995：25.
[2]沈连生.神农本草经中药彩色图谱[M].北京：中国中医药出版社,1996.
[3]国家药典委员会.中华人民共和国药典·一部[M].北京：中国医药科技出版社，2000.
[4]于淼,韩佳瑞,焦拥政,等.中药及中药复方剂量阈、治疗窗的构建及思考[J].中医杂志,2011,52(20):17931794.
[5]仝小林,穆兰澄,吴义春,等.药食两用中药的大剂量临床应用[J].中医杂志,2009,50(S1):98101.

相似文献/References:

[1]孙鑫,钱会南.《神农本草经》与统编中药学教材中药理论体系框架对比研究[J].环球中医药,2017,10(12):1477.[doi:10.3969/j.issn.1674-1749.2017.12.015]

备注/Memo

备注/Memo:
基金项目：国家重点基础研究发展计划(973计划)（2010CB530600)）
作者单位：100053 北京，中国中医科学院广安门医院内分泌科［姬航宇（博士研究生）、仝小林、陈欣燕（博士研究生）、赵林华、焦拥政］；北京中医药大学研究生院[姬航宇(博士研究生)、陈欣燕（博士研究生）]；河南中医学院第二临床医学院（韩佳瑞）
作者简介：姬航宇（1984- ），博士研究生。研究方向：方药量效关系研究。Email：echo.ji2008@gmail.com
通讯作者：焦拥政（1972- ），博士，副研究员。研究方向：方药量效关系研究。Email：yzhjiao@126.com
更新日期/Last Update: 1900-01-01