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[1]丁剑波,张佳莹,田一梅,等.喜炎平注射液治疗手足口病的Meta分析[J].环球中医药,2013,6(08):585-0.
　DING Jian bo,ZHANG Jia ying,TIAN Yi mei,et al.Metaanalysis of Xiyanping injection in the treatment of handfootmouth disease[J].,2013,6(08):585-0.
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喜炎平注射液治疗手足口病的Meta分析()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第6卷
期数:
2013年08期
页码:
585-0
栏目:
论著
出版日期:
2013-08-06

文章信息/Info

Title:
Metaanalysis of Xiyanping injection in the treatment of handfootmouth disease
作者:
丁剑波;张佳莹;田一梅;刘丹;李秀惠;
Author(s):
DING Jianbo; ZHANG Jiaying; TIAN Yimei; et al.
Department of Integrated TCM and Western Medicine，Beijing YouAn Hospital，Capital Medical University, Beijing 100069, China
关键词:
喜炎平注射液; 手足口病; 系统评价; Meta分析
Keywords:
Xiyanping injection; Handfootmouth disease(HFMD); System evaluation; Metaanalysis
分类号:
R1951
DOI:
-
文献标志码:
A
摘要:
目的系统评价喜炎平注射液治疗儿童手足口病的疗效和安全性。方法通过检索中国期刊全文数据库、中文科技期刊全文数据库、万方数据库收集喜炎平注射液治疗手足口病的随机对照试验文献,用Jadad评分表评价纳入文献的质量,用RevMan5.0软件对纳入的文献进行Meta分析。结果最终纳入文献共11篇,共计病例数1241例,Meta分析结果显示,喜炎平注射液加基础治疗与利巴韦林注射液加基础治疗相比,退热时间缩短1.85天,退疹时间缩短1.51天,总病程时间缩短2.55天,并且均有统计学意义(P<0.00001),尚未见报道喜炎平注射液相关的严重不良反应。结论喜炎平注射液治疗手足口病临床疗效明确,且未见严重不良反应,但尚需设计严谨的随机对照试验来进一步验证。
Abstract:
ObjectiveTo evaluate the efficacy and safety of Xiyanping injection for treating handfootmouth disease (HFMD) systematically. Methods Literatures about randomized controlled trials of Xiyanping injection for treating HFMD were collected by China National Knowledge Internet, Chinese science and technology periodical fulltext database and ChianInfo. The quality of the literatures was assessed by Jadad rating scale, and the data was analysis by RevMan 5.0 software. Results 11 poorquality studies were included，involving 1241 participants. Metaanalysis showed that the days of Xiyanping injection combined basic therapy group on fever, rash and total duration were shorter than those of ribavirin combined basic therapy group, and the differences were statistically significant（P＜0.0001）. Serious adverse reaction of Xiyanping injection was not showed. Conclusions Xiyanping injection showed better therapeutic effect on HFMD. But the quality of the trials is poor. And standard study may be needed.

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　HONG Ke,NIE Fan,NIE Guang,et al.Etiology and mechanism and syndromes differenation in periods on 2024 HFMD patients[J].,2012,5(08):332.
[9]李华东,周海兰,韩晓群,等.手足口病128例临床特征分析及临床疗效观察[J].环球中医药,2012,5(05):378.

备注/Memo

备注/Memo:
基金项目：国家中医药管理局2009年中医药行业科研专项(2009070013)
作者单位：100069 首都医科大学附属北京佑安医院中西医结合科［丁剑波、张佳莹、田一梅、刘丹（硕士研究生）、李秀惠］
作者简介：丁剑波（1987-），硕士。研究方向：中西医结合防治传染病。Email：jianbo1@163.com
通讯作者：李秀惠（1960-），女，教授，博士生导师。研究方向：中西医结合防治传染病。Email：lixiuhui@sohu.com
更新日期/Last Update: 1900-01-01