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[1]张喆 刘瑜 王微等.中西医结合治疗高脂血症性急性胰腺炎的临床观察[J].环球中医药,2014,7(06):430-0.
　ZHANG Zhe,LIU Yu,WANG Wei,et al.Treating hyperlipidemic acute pancreatitis with integrated traditional Chinese medicine and western medicine: a clinical research[J].,2014,7(06):430-0.
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中西医结合治疗高脂血症性急性胰腺炎的临床观察()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第7卷
期数:
2014年06期
页码:
430-0
栏目:
论著
出版日期:
2014-06-06

文章信息/Info

Title:
Treating hyperlipidemic acute pancreatitis with integrated traditional Chinese medicine and western medicine: a clinical research
作者:
张喆 刘瑜 王微等
Author(s):
ZHANG Zhe;  LIU Yu;  WANG Wei;  et al.
Department of TCM Gastroenterology, ChinaJapan friendship hospital, Beijing 100029, China
关键词:
高脂血症; 急性胰腺炎; 中西医结合治疗
Keywords:
Hyperlipidaemia; Acute pancreatitis; The integrated treatment with TCM and standard therapies
分类号:
R6575+1
DOI:
-
文献标志码:
A
摘要:
目的观察中西医结合治疗对高脂血症性急性胰腺炎的干预效果。方法将72例高脂血症性急性胰腺炎患者随机分为治疗组和对照组各36例，在西医规范治疗的基础上中西医结合治疗组给予中药内服并灌肠治疗，记录腹痛缓解时间和血淀粉酶恢复正常时间，7天后评价临床疗效，并记录甘油三酯及总胆固醇变化，并对记录进行缝隙评价。结果两组临床疗效无差异（P＞005），中西医治疗组腹痛缓解时间和血淀粉酶恢复时间均短于对照组（P＜005）；治疗后两组患者甘油三酯均较治疗前下降（P＜001），但两组对比治疗组下降更明显（P＜005）；局部并发症发生率治疗组较对照组低，但无统计学差异（P＞005）。结论中西医结合治疗较单纯西医治疗可更快的改善高脂血症性急性胰腺炎的腹痛症状和降低其血淀粉酶水平，更好的降低甘油三酯。
Abstract:
ObjectiveTo observe the clinical effect of the integrated treatment with traditional Chinese medicine (TCM) and standard therapies on hyperlipidemic acute pancreatitis. Methods 72 patients with hyperlipidemia acute pancreatitis were randomly divided into treatment group and control group. Both groups received standard western therapies and 36 cases in treatment group received additionally the integrated treatment with TCM. The time of abdominal pain relief, recovery time of serum amylase, and changes in triglycerides and total cholesterol were recorded and analyzed. ResultsThere was no statistical difference in clinical effect of the two groups(P＞005). The time of pain relief and recovery time of serum amylase of treatment group was shorter than that of control group (P＜005 or P＜0.01). The level of triglycerides and total cholesterol of treatment group were lower than that of the other group after treatment. The incidence of local complications in treatment group was lower than that of control group, but there was no statistical difference (P＞005). ConclusionThe speed of main symptom relief and serum amylase level descending was faster, meanwhile the level of triglycerides was improvement better with the integrated treatment with TCM.

参考文献/References:

［1］刘忠铭．高脂血症性急性胰腺炎诊断及治疗［J］．重庆医学，2010，30（6）：670671．
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［3］中华人民共和国卫生部．中药新药临床研究指导原则（第一辑）［S］．北京：中华人民共和国卫生部制定发布，1993：142144．
［4］Working Group IAP/APA Acute Pancreatitis Guidelines. IAP/APA evidencebased guidelines for the management of acute pancreatitis［J］. Pancreatology : Official Journal of the Internatio, 2013, 13(4 Suppl 2): e115.
［5］林旭红，李永渝．急性胰腺炎发病机制及相关治疗的研究进展［J］． 中国病理生理杂志，2010，26（5）：10291032．
［6］张帆，郭强，张渊智．高脂血症、微循环障碍与急性胰腺炎关系的探讨［J］．胃肠病学和肝病学杂志，2011，20（3）：275278．
［7］EATOCK F C, CHONG P, MENEZES N, et al. A randomized study of early nasogastric versus nasojejunal feeding in severe acute pancreatitis［J］. The American Journal of Gastroenterology, 2005, 100(2): 432439.
［8］KUMAR A, SINGH N, PRAKASH S, et al. Early enteral nutrition in severe acute pancreatitis: a prospective randomized controlled trial comparing nasojejunal and nasogastric routes［J］. Journal of Clinical Gastroenterology, 2006, 40(5): 431434.

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备注/Memo

备注/Memo:

作者单位：100029 北京，中日友好医院中医消化科
作者简介：张喆（1980-），博士，主治医师。研究方向：中西医结合治疗消化系统疾病。Email：zhangzhebj@163.com
通讯作者：符思（1957-），教授，主任医师，硕士生导师，中华中医药学会老年病分会常务委员，中国中西医结合学会消化系统疾病专业委员会委员，世界中医药联合会消化病专业委员会理事。研究方向：中西医结合治疗消化系统疾病。Email：fusizryhyy@126.com
更新日期/Last Update: 1900-01-01