|本期目录/Table of Contents|

[1]李得民,疏欣杨,张金秋,等.中药贴敷疗法辅助治疗慢性阻塞性肺疾病急性加重期相关性胸腔积液的疗效观察[J].环球中医药,2017,10(04):397-400.[doi:10.3969/j.issn.1674-1749.2017.04.004]
　LI Demin,SHU Xinyang,ZHANG Jinqiu,et al.Efficacy of external Chinese medicine therapy for pleural effusion associated with acute exacerbation of chronic obstructive pulmonary disease[J].,2017,10(04):397-400.[doi:10.3969/j.issn.1674-1749.2017.04.004]
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中药贴敷疗法辅助治疗慢性阻塞性肺疾病急性加重期相关性胸腔积液的疗效观察()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第10卷
期数:
2017年04期
页码:
397-400
栏目:
COPD研究专题
出版日期:
2017-04-06

文章信息/Info

Title:
Efficacy of external Chinese medicine therapy for pleural effusion associated with acute exacerbation of chronic obstructive pulmonary disease
作者:
李得民; 疏欣杨; 张金秋; 孙爱华; 张纾难
100029 北京,国家呼吸疾病临床研究中心 中日友好医院呼吸中心 中日友好医院中医肺病科
Author(s):
LI Demin; SHU Xinyang; ZHANG Jinqiu; et al.
Pulmonary Disease Department,China-Japan Friendship Hospital,Beijing 100029,China
关键词:
慢性阻塞性肺疾病急性加重期;  胸腔积液;  外治法;  穴位贴敷
Keywords:
Acute exacerbation of chronic obstructive pulmonary disease;  Pleural effusion;  External Chinese medicine therapy;  Acupoint application
分类号:
R256.1
DOI:
10.3969/j.issn.1674-1749.2017.04.004
文献标志码:
A
摘要:
目的 观察中药贴敷疗法辅助治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)相关性胸腔积液的有效性及安全性。方法 采用回顾性研究方法,根据入院治疗方法的不同,将35例AECOPD相关性胸腔积液患者分为对照组18例,观察组17例,两组均采用中西医结合基础治疗,观察组辅助中药贴敷治疗。疗程10～14天。治疗结束后观察两组的临床疗效,并比较两组慢阻肺患者自我评估测试问卷评分、血浆D-二聚体水平治疗前后变化及住院天数。结果 观察组有效率为94.12%,对照组为61.11%,两组差异有统计学意义(P＜0.05)。治疗结束后观察组慢阻肺患者自我评估测试问卷评分改善更显著,差异有统计学意义(P＜0.05); 与对照组相比,观察组血浆D-二聚体水平降低更明显,差异有统计学意义(P＜0.05)。同时,中药贴敷治疗可显著缩短AECOPD相关性胸腔积液患者的住院天数,差异有统计学意义(P＜0.05)。结论 中药贴敷疗法辅助治疗AECOPD相关性胸腔积液疗效显著,安全可靠,值得今后临床开展前瞻、随机、对照研究以进一步为临床应用提供循证依据。
Abstract:
Objective To observe the effectiveness and safety of external Chinese medicine therapy in the treatment of pleural effusion associated with acute exacerbation of chronic obstructive pulmonary disease(AECOPD). Methods Retrospective study method was used, 35 cases of pleural effusion associated with AECOPD were divided into control group(18 cases)and observation group(17 cases)according to the different treatment methods, 2 groups were used traditional Chinese medicine and Western medicine combined with routine therapy, observation group combined with Chinese herbs paste treatment application. 10～14 days as one therapeutic course. After treatment, the clinical efficacy of the 2 groups were observed, and CAT questionnaire score, plasma D-Dimer levels and hospital days were compared. Results The effective rate of the observation group was 94.12%, the control group was 61.11%, and the difference between the 2 groups was statistically significant(P＜0.05). After treatment, the CAT questionnaire scores of observation group was improved more significantly(P＜0.05); compared with the control group, the level of D-Dimer in the observation group was decreased significantly(P＜0.05). At the same time, the application of traditional Chinese medicine treatment can significantly shorten the length of hospital stay in patients with pleural effusion associated with AECOPD, the results had statistical significance(P＜0.05). Conclusion The therapeutic effect of traditional Chinese medicine plaster therapy on pleural effusion associated with AECOPD is significant, safe and reliable, and it is worthy to conduct prospective study, randomized study, controlled study in the future to provide evidence-based basis for clinical application.

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备注/Memo

备注/Memo:
基金项目: 国家自然科学基金(81541173); 国家临床重点专科
作者简介: 李得民(1982- ),博士,主治医师。研究方向:中西医结合呼吸病学及中医特色治疗。E-mail:deminli2008@sina.com
通信作者: 张纾难(1963- ),博士,主任医师,教授,博士生导师。研究方向:中医药防治呼吸系统疾病研究。E-mail:shunan_zhang2010@qq.com
更新日期/Last Update: 2017-04-06