|本期目录/Table of Contents|

[1]贺梅娟,陈宇征,杨晋翔,等.基于关联规则的慢性萎缩性胃炎癌前病变用药规律探讨[J].环球中医药,2017,10(04):406-410.[doi:10.3969/j.issn.1674-1749.2017.04.006]
　HE Meijuan,CHEN Yuzheng,YANG Jinxiang,et al.Study on the regularity of the treatment of precancerous lesions of chronic atrophic gastritis based on association rules[J].,2017,10(04):406-410.[doi:10.3969/j.issn.1674-1749.2017.04.006]
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基于关联规则的慢性萎缩性胃炎癌前病变用药规律探讨()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第10卷
期数:
2017年04期
页码:
406-410
栏目:
论著
出版日期:
2017-04-06

文章信息/Info

Title:
Study on the regularity of the treatment of precancerous lesions of chronic atrophic gastritis based on association rules
作者:
贺梅娟; 陈宇征; 杨晋翔; 安静
100165 北京市丰台区卢沟桥医院中医科(贺梅娟、陈宇征); 北京中医药大学第三附属医院消化科(杨晋翔、安静)
Author(s):
HE Meijuan;  CHEN Yuzheng;  YANG Jinxiang;  et al.
Department of traditional Chinese medicine, Beijing Fengtai Lugouqiao Hospital,Beijing 100165,China
关键词:
慢性萎缩性胃炎癌前病变;  用药规律;  关联分析
Keywords:
Chronic atrophic gastritis precancerous lesions;  Prescription regularity;  Association analysis
分类号:
R573.3
DOI:
10.3969/j.issn.1674-1749.2017.04.006
文献标志码:
A
摘要:
目的 探讨基于数据挖掘的中医药治疗慢性萎缩性胃炎癌前病变的处方用药规律。方法 检索自1994年至2014年1月中国生物医学文献数据库(CBM)、中国知网(CNKI)、万方、维普中文科技期刊全文数据库(VIP),收集慢性萎缩性胃炎癌前病变中医辨证治疗文献,进行整理和计量分析,对常见证型药物配伍规律进行关联规则分析。结果 共纳入相关文献38篇,计200条辨证用药数据。常见证型出现频率由高到低依次为脾胃虚弱、肝胃不和、胃阴不足、脾胃湿热、胃络瘀血。本病病机特点为本虚标实、虚实夹杂,本虚为脾胃气虚和/或阴虚,标实为瘀血邪毒。辨证治疗使用药物主要包括健脾、理气、化湿、清热、活血及养阴六类。结论 数据挖掘能够充分反应中医药治疗慢性萎缩性胃炎癌前病变的处方用药规律,对于临床用药和中药处方开发具有重要的意义。
Abstract:
Objective To explore the application of traditional Chinese medicine in the treatment of chronic atrophic gastritis precancerous lesion based on data mining. Methods CBM, CNKI, Wan Fang, VIP database(1994～2014 January), the literature of TCM in treatment for precancerous lesions of chronic atrophic gastritis was collected. The collation and quantitative analysis were carried out, and the association rules drug compatibility was analyzed. Results A total of 38 articles were included and there were 200 TCM syndrome differentiation and treatment data were included. The order of common syndromes from high to low was weakness of the spleen and the stomach, liver-stomach disharmony, stomach yin deficiency, damp heat in the spleen and the stomach, stagnated blood of stomach meridian. Pathogenesis of this disease was asthenia in origin and asthenia in superficiality, intermingled deficiency and excess, spleen stomach qi deficiencyand/or yin deficiency was benxu,blood stasis toxin was biaoshi. Treatment of syndrome differentiation included tonifying spleen,regulating qi,resolving dampness,clearing heat,activating blood and nourishing yin.Conclusions Data mining can fully reflect medicine law for formula of traditional Chinese medicine in the treatment of chronic atrophic gastritis precancerous lesions,and has important significance for clinical medication and prescription development of traditional Chinese medicine.

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备注/Memo

备注/Memo:
基金项目: 国家自然科学基金面上项目(81173232)
作者简介: 贺梅娟(1980- ),女,博士,主治医师。研究方向:脾胃病中医药防治。E-mail:444914128@qq.com
更新日期/Last Update: 2017-04-06