|本期目录/Table of Contents|

[1]何希瑞,李倩,张春玲,等.胡黄连化学成分及单体化合物药理活性研究新进展[J].环球中医药,2012,5(09):708-0.
 HE Xi rui,LI Qian,ZHANG Chun ling,et al.Phytochemical andbiological studies on Picrorrhiza scrophularaeflora Pennell[J].,2012,5(09):708-0.
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胡黄连化学成分及单体化合物药理活性研究新进展()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第5卷
期数:
2012年09期
页码:
708-0
栏目:
综述
出版日期:
2012-09-06

文章信息/Info

Title:
Phytochemical andbiological studies on Picrorrhiza scrophularaeflora Pennell
作者:
何希瑞; 李倩; 张春玲; 常育; 姚宏; 赵婷;
Author(s):
HE Xirui LI Qian ZHANG Chunling et al.
Department of Pharmacy,Red Cross Hospital, Xi'an Jiaotong University Medical College, Xi’an 710054,China
关键词:
胡黄连 环烯醚萜苷 保肝
Keywords:
Picrorrhiza scrophularaefloraIridoid glycosidesHepatoprotection
分类号:
R285
DOI:
-
文献标志码:
A
摘要:
胡黄连(Picrorrhiza scrophularaeflora Pennell)是常用中药,医药前景良好。目前,已经从胡黄连中分离得到70多种化合物,其中主要成分是环烯醚萜苷、苯乙醇苷和酚苷。药理实验研究表明,胡黄连单体化合物具有广泛的药理作用,尤其是在保肝利胆、抗菌消炎、保护受损的神经细胞及凋亡的心肌细胞等方面具有显著的效果。本文通过查阅相关文献,主要从化学成分、单体化合物药理活性方面对胡黄连国内外研究概况进行整理和分析,以期为胡黄连药用资源的合理开发和利用提供理论依据。
Abstract:
Picrorrhiza scrophularaeflora Pennell is commonly used as the traditional Chinese medicine in China. Up to now, more than 70 compounds have been isolated and identified, and the iridoid glycosides, phenylethanoid glycosides and phenol glycosides are the main constituent. The monomer compounds from P. scrophularaeflora possessed wide pharmacological actions, especially in hepatoprotection, antiinflammatory, nerve growth enhancement and cardiomyocytes protection, etc. The present paper reviews the chemical compounds, the biological activities of P. scrophularaeflora, which would provide references for development and utilization of the plant.

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备注/Memo

备注/Memo:

作者单位: 710054 西安交通大学医学院附属红会医院药学部作者信息: 何希瑞(1985- ), 硕士, 药师。研究方向:临床药理与新药研发。Email: xiruihe6105194@163.com
更新日期/Last Update: 1900-01-01