|本期目录/Table of Contents|

[1]邹萍 陈万瑛 张婷等.人参皂苷 Rg3 抗宫颈癌作用机制的研究进展[J].环球中医药,2014,7(04):304-0.
　ZOU Ping,CHEN Wan ying,ZHANG Ting,et al.Research progress on mechanism of ginsenosides Rg3 against cervical cancer[J].,2014,7(04):304-0.
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人参皂苷 Rg3 抗宫颈癌作用机制的研究进展()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第7卷
期数:
2014年04期
页码:
304-0
栏目:
综述
出版日期:
2014-04-06

文章信息/Info

Title:
Research progress on mechanism of ginsenosides Rg3 against cervical cancer
作者:
邹萍 陈万瑛 张婷等
Author(s):
ZOU Ping; CHEN Wanying; ZHANG Ting; et al.
Wuxi maternal and Child Health Hospital Affiliated to Nanjing Medical University，Wuxi 214002, China
关键词:
人参皂苷:6642; 宫颈癌:5151; 作用机制:4191; 研究进展:3431
Keywords:
Ginsenosides; Cervical cancer; Mechanism
分类号:
R285
DOI:
-
文献标志码:
A
摘要:
宫颈癌是妇科最常见的恶性肿瘤，目前临床使用的治疗方法均有副作用。随着医药学的发展，天然药物在宫颈癌疗效、治疗靶点方面的优势越来越受到研究者的重视。国内外实验研究以及流行病学调查均表明传统的滋补养生名贵中草药人参的主要活性成分人参皂苷Rg3在抗宫颈癌方面有有效的作用，也有研究发现其能使化疗增敏。为进一步系统的了解人参皂苷Rg3在治疗宫颈癌方面的作用，本文从促进宫颈癌细胞凋亡，抑制宫颈癌细胞增殖，抑制宫颈癌新生血管形成以及提高免疫力等几个方面对人参皂苷Rg3抗宫颈癌作用机制进行综述。
Abstract:
Cervical cancer is the most common malignant gynecological tumor in Gynecology. Current clinical treatment methods all have worrying side effects. With the rapid development of biomedicine and pharmacy, the advantages of natural medicine in the treatment of cervical cancer therapeutic target has been attached more and more importance by researchers. Ginseng is a traditional Chinese tonic herb which is rare and luxury. At present, domestic/ overseas experimental research and epidemiological investigation all show that the main active ingredients named Rg3 has an effective role in anti cervical cancer. There are also some other studies that show that Ginsenoside Rg3 can play the role of chemotherapy sensitization. For further understanding of ginsenoside Rg3 in the treatment of cervical cancer, this paper, reviews the mechanism of Ginsenoside Rg3 against cervical cancer as follows: Ginsenoside Rg3 can promote the apoptosis of cervical cancer cells, inhibit the proliferation of cervical cancer cells, promote the inhibition of cervical carcinoma angiogenesis, and improve the immunity of patients and so on.

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备注/Memo

备注/Memo:
基金项目：国家自然科学青年基金（81202043）；江苏省“科教兴卫工程”专项经费资助项目（RC2011033）；江苏省中医药局科技项目(LB11048)；新疆克州科技项目（20131327）
作者单位：214002 无锡，南京医科大学附属无锡妇幼保健院检验科（邹萍、张婷、陈道桢）；新疆阿合奇县人民医院检验科（陈万瑛）
作者简介：邹萍（1987- ），女，硕士，初级检验师。研究方向：妇科肿瘤。Email：yezihenhaohenhaode@126.com 通信作者：陈道桢(1971- )，博士，副教授，副主任技师，硕士生导师。研究方向：妇科肿瘤生物治疗。Email：chendaozhen@163.com
更新日期/Last Update: 1900-01-01