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[1]左茹 曹雪滨 张文生.黄连素药理作用研究进展[J].环球中医药,2014,7(07):568-0.
　ZUO Ru,CAO Xue-bin,ZHANG Wen-sheng.The progress of berberine's pharmacological effects[J].,2014,7(07):568-0.
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黄连素药理作用研究进展()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第7卷
期数:
2014年07期
页码:
568-0
栏目:
综述
出版日期:
2014-07-06

文章信息/Info

Title:
The progress of berberine's pharmacological effects
作者:
左茹 曹雪滨 张文生
Author(s):
ZUO Ru;  CAO Xue-bin;  ZHANG Wen-sheng
College of traditional Chinese medicine Hebei University, Baoding 071000, China
关键词:
黄连素;  药理作用;  研究进展
Keywords:
Berberine;  Pharmacological effects;  Progress
分类号:
R285
DOI:
-
文献标志码:
A
摘要:
黄连素又称盐酸小檗碱,是从中药黄连中提取的一种天然的异喹啉类生物碱,具有广泛的药理作用,包括抗炎、抗癌、抑菌、降脂、降糖等。实验研究及临床报道发现黄连素对神经系统、内分泌系统、消化系统、循环系统、呼吸系统等多个系统的疾病均具有治疗作用。本文就黄连素对各系统疾病的药理作用进行总结,以期为研究黄连素治疗相关疾病提供借鉴。
Abstract:
Berberine, also known as berberine hydrochloride, is extracted from traditional Chinese herb, Coptis chinensis Franch, which is a natural isoquinoline alkaloid and has extensive pharmacological effects, including anti-inflammatory, anti-cancer, bacteriostat, lipid-lowering, hypoglycemic, etc. Amount of experimental studies and clinical reports found that berberine has therapeutic effects on the diseases of nervous system, endocrine system, digestive system, circulation system, respiratory system, and other systems. This article summarized the pharmacological effects of berberine on various diseases in order to provide references for the treatment of diseases using berberine.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金(81274118); 科技部“重大新药创制”科技重大专项(2012ZX09103-201)
作者单位:071000 保定,河北大学中医学院[左茹(硕士研究生)]; 中国人民解放军第252医院心血管内科(左茹、曹雪滨); 北京师范大学教育部天然药物工程研究中心(左茹、张文生)
作者简介:左茹(1987- ),女,2011级在读硕士研究生。研究方向:中西医结合治疗心脑血管病。E-mail: zuoru19871124@163.com
通讯作者:张文生(1966- ),博士,教授,博士生导师。研究方向:神经退行性疾病分子机制及神经药理。E-mail: zws@bnu.edu.cn
更新日期/Last Update: 1900-01-01