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[1]许凉凉,伊辛,魏文浩,等.藏药结血蒿挥发油提取工艺研究[J].环球中医药,2015,8(03):329-331.[doi:10.3969/j.issn.1674-1749.2015.03.016]
　XU Liang-liang,YI Xin,WEI Wen-hao,et al.Extraction process study for essential oil of Artemisia vestita Wall. ex Bess[J].,2015,8(03):329-331.[doi:10.3969/j.issn.1674-1749.2015.03.016]
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藏药结血蒿挥发油提取工艺研究()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第8卷
期数:
2015年03期
页码:
329-331
栏目:
论著
出版日期:
2015-03-06

文章信息/Info

Title:
Extraction process study for essential oil of Artemisia vestita Wall. ex Bess
作者:
许凉凉; 伊辛; 魏文浩; 尹雪雁; 蔡程科
100102 北京中医药大学中药学院[许凉凉(硕士研究生)、伊辛(硕士研究生)、魏文浩(硕士研究生)、尹雪雁(硕士研究生)],研究生院(蔡程科)
Author(s):
XU Liang-liang;  YI Xin;  WEI Wen-hao; et al.
School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China Corresponding author:CAI Cheng-ke,E-mail:cck98@126.com
关键词:
结血蒿;  藏药;  挥发油;  正交实验
Keywords:
Artemisia vestita Wall;  Tibetan medicine;  Essential oil;  Orthogonal design
分类号:
R284.2
DOI:
10.3969/j.issn.1674-1749.2015.03.016
文献标志码:
A
摘要:
目的 通过正交设计优选藏药结血蒿挥发油提取工艺,确定结血蒿挥发油提取最佳工艺。方法 采用水蒸气蒸馏法提取结血蒿挥发油,设计L9(34)的正交表,以出油率作为考察指标,考察加水量、浸泡时间、提取时间三个因素对结血蒿挥发油提取的影响。由于结血蒿浸膏也是所需功效成分,因此同时考察三个因素对浸膏得率的影响。结果 对结血蒿挥发油出油率,浸泡时间和提取时间有显著影响(P<0.05),有统计学意义,而加水量对其没有显著影响(P>0.05); 对结血蒿浸膏得率,加水量对其具有显著影响(P<0.05),而浸泡时间、提取时间对其无显著影响(P>0.05),无统计学意义。经验证最终确定结血蒿挥发油最佳提取工艺为加水量18倍,浸泡1小时,提取5小时,出油率可达0.66%,浸膏得率可达23.0%。结论 通过实验研究证明该提取工艺可靠合理,可用于结血蒿挥发油的提取。
Abstract:
Objective To optimize the extraction press for essential oil of Artemisia vestita Wall through orthogonal design and to determine the best extraction process. Methods Artemisia vestita Wall oil was extracted by steam distillation extraction, Orthogonal test was used to evaluate the volume of added water, soaking time and extracting time using oil extraction rate as the evaluating indicator. Because extract of Artemisia vestita Wall is also the functional component needed, to investigating the influence of three factors on the extraction rate. Results As for oil extraction rate, soaking time and extracting time had obvious significance(P<0.05)with statistical significance, while the volume of added water had not statistical significance(P>0.05); As for extraction rate, only the volume of added water had obvious significance(P<0.05)with statistical significance, soaking time and extracting time had not obvious significance. The best extraction press for essential oil of Artemisia vestita Wall was as follows:18-fold water added, soaked for 1 hour, extracted for 5 hours. Oil extraction rate was 0.66%, extraction rate was 23.0%. Conclusion The experimental study showed that the extraction process was reliable and reasonable, it can be used for essential oil of Artemisia vestita Wall.

参考文献/References:

[1] 巴桑德吉,次尼贡布.藏药结血蒿膏质量标准的研究[J].中国民族医药杂志,2010,16(12):52.
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[3]强巴赤烈,占堆,次仁巴珠.中华本草藏药卷[M].上海:上海科技出版社,2002:202-203.
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备注/Memo

备注/Memo:
基金项目:北京中医药大学自主课题(2013-ZYY- 01); 北京中医药大学科研创新团队项目(2011-CXTD-13) 作者简介:许凉凉(1989- ),2012级在读硕士研究生。研究方向:中药新剂型与新制剂。E-mail:18811502803@163.com 通讯作者:蔡程科(1971- ),博士,副教授。研究方向:中药新剂型与新制剂。E-mail:cck98@126.com
更新日期/Last Update: 2015-03-20