|本期目录/Table of Contents|

[1]孙莹 梁晓春.中药对糖尿病周围神经病变中肿瘤坏死因子α的干预作用概述[J].环球中医药,2017,10(03):373-376.[doi:10.3969/j.issn.1674-1749.2017.03.036]
　SUN Ying,LIANG Xiaochun..Review on effect of traditional Chinese medicine on tumor necrosis factor-α in diabetic peripheral neuropathy[J].,2017,10(03):373-376.[doi:10.3969/j.issn.1674-1749.2017.03.036]
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中药对糖尿病周围神经病变中肿瘤坏死因子α的干预作用概述()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第10卷
期数:
2017年03期
页码:
373-376
栏目:
综述
出版日期:
2017-03-06

文章信息/Info

Title:
Review on effect of traditional Chinese medicine on tumor necrosis factor-α in diabetic peripheral neuropathy
作者:
孙莹 梁晓春
100730 北京,中国医学科学院北京协和医学院中医科[孙莹(博士研究生)、梁晓春]
Author(s):
SUN Ying;  LIANG Xiaochun.
Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Beijing 100730, China
关键词:
中药;  糖尿病周围神经病变;  肿瘤坏死因子
Keywords:
Traditional Chinese medicine;  Diabetic peripheral neuropathy;  Tumor necrosis factor-α
分类号:
R587.1
DOI:
10.3969/j.issn.1674-1749.2017.03.036
文献标志码:
A
摘要:
糖尿病周围神经病变(diabetic peripheral neuropathy,DPN)已成为糖尿病致死、致残的重要原因,研究发现肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)在DPN的发生、发展中起到了负性作用,而中药可以通过抑制TNF-α起到改善周围神经传导速度,抑制周围神经损伤,缓解神经痛的作用。因此本文综述了近年来研究发现的TNF-α在DPN中的损伤作用及中药通过干预TNF-α起到的抑制DPN作用。
Abstract:
Diabetic peripheral neuropathy(DPN)has become the most important reason of death and disability in diabetes. It has been found that tumor necrosis factor -α(TNF-α)plays a negative role in the development of DPN. Research has revealed that traditional Chinese medicine(TCM)could inhibit TNF-α to improve peripheral nerve conduction velocity, reduce peripheral nerve injury, relieve neuropathic pain. This paper reviewed recent studies about the injury effect of TNF-α in DPN and the therapeutic effect of TCM in DPN by intervening TNF-α.

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备注/Memo

备注/Memo:
基金项目: 国家自然科学基金(81473639); 北京市自然科学基金(7122147)
作者简介: 孙莹(1986- ),女,2014级在读博士研究生。研究方向:中西医结合临床。E-mail:sunying1214@sina.com
通信作者: 梁晓春(1956- ),女,硕士,教授。研究方向:中西医结合治疗糖尿病。E-mail:xcliang@vip.sina.com
更新日期/Last Update: 2017-03-06