|本期目录/Table of Contents|

[1]龙晓华,王乐鹏,单体亮,等.基于数据挖掘的郑钦安用药规律研究[J].环球中医药,2015,8(05):540-545.[doi:10.3969/j.issn.16741749.2015.05.007]
　LONG Xiao hua,WANG Le peng,SHAN Ti liang,et al.Study on the medication regularities of ZHENG Qinan based on data mining[J].,2015,8(05):540-545.[doi:10.3969/j.issn.16741749.2015.05.007]
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基于数据挖掘的郑钦安用药规律研究()
     
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《环球中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
第8卷
期数:
2015年05期
页码:
540-545
栏目:
论著
出版日期:
2015-05-06

文章信息/Info

Title:
Study on the medication regularities of ZHENG Qinan based on data mining
作者:
龙晓华; 王乐鹏; 单体亮; 等
100029北京中医药大学基础医学院
Author(s):
LONG Xiaohua;  WANG Lepeng;  SHAN Tiliang;  et;  al.
School of Basic Medical Sciences, Beijing University of Chinese Medicine， Beijing,100029,China Corresponding author: MA Shuran, Email：mashuran64@ sina.com
关键词:
数据挖掘; 郑钦安; 用药规律
Keywords:
Data mining; ZHENG Qinan; Medication regularity
分类号:
R249
DOI:
10.3969/j.issn.16741749.2015.05.007
文献标志码:
A
摘要:
目的利用现代统计学和数据挖掘方法，挖掘郑钦安的用药规律，为深入研究郑钦安的临床用药规律和学术思想提供统计学依据。方法 从《医理真传》与《医法圆通》中收集组成明确的方剂。利用Excel建立方药数据库，采用SPSS 170和clementine 120软件对数据进行描述统计分析、双变量相关性分析、关联规则分析和聚类分析。结果方剂来源医著不少于3次者15种，来源于《伤寒论》的方剂最多，为42首。使用频次不少于10次的中药32味，排在前10味的中药主要是桂枝汤和四君子汤的药物组成。相关系数大于02的药对30对。关联规则分析提取出84条规则。聚类分析得出6组药和7对核心药对。结论发现郑钦安在用药上具有如下几个特点：（1）法宗伤寒，推崇仲景；（2）辨分二纲，药有阴阳；（3）善补脾胃，协和营卫；（4）配伍灵活，用药圆通。
Abstract:
ObjectiveTo excavate the medication regularities of ZHENG Qinan by means of modern statistics and data mining methods, and provide a statistical basis for indepth study of ZHENGs clinical medication regularities and academic thoughts. MethodsPrescriptions with specific composition were collected from the True Principles of Medical Science (Yi Li Zhen Zhuan)and Flexibility of Medical Method (Yi Fa Yuan Tong). Excel is used to set up the prescriptions database, SPSS170 and clementine120 softwares were used to do descriptive statistical analysis, bivariate correlation analysis, association rules analysis, and cluster analysis. Results15 prescriptions come from at least three medical books, prescriptions from Treatise on Cold Damages rank most, totalling up to 4232 kinds of Chinese medicinals are used not less than 10 times. The Chinese medicinals that rank top 10 are mainly the composition of Guizhi decoction and Sijunzi decoction. 30 herb pairs correlation coefficient is greater than 02. Association rules analysis has extracted out 84 rules. 6 groups of medicinals and 7 core herb pairs have been extracted by cluster analysis. ConclusionIt is found that ZHENGs drug application has the following characteristics: (1) his medication regularities follow Cold Damages, and respect Zhong Jing; (2) pattern diagnosis and medicines both should be distinguished by yin and yang; (3) good at invigorating the spleen and stomach, coordinating nutrient qi and defense qi; (4) flexible compatibility and drug application.

参考文献/References:

［1］唐步祺.郑钦安医书阐释[M].四川：巴蜀书社，2006:19.
[2]高学敏.中药学[M].北京：中国中医药出版社，2007:1524.
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[4]薛薇，陈欢歌.基于Clementine的数据挖掘[M].北京：中国人民大学出版社，2012:435450，398.
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[6]郑钦安.中医火神派三书[M].周鸿飞点校.北京：学苑出版社，2007:124，30，237238.
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备注/Memo

备注/Memo:
基金项目：北京中医药大学科研创新团队项目（2011CXTD01）；国家中医药管理局刘燕池名医传承工作室建设项目（01/010002607）；北京市中医药管理局刘燕池名医传承工作站建设项目(2009SZC24） 作者单位：100029北京中医药大学基础医学院\[龙晓华（硕士研究生）、王乐鹏（博士研究生）、单体亮（硕士研究生）、马淑然\] 作者简介：龙晓华（1990- ），2013级在读硕士研究生。研究方向：天人相应理论与临床。Email：1090292569@qq.com 通讯作者：马淑然（1964- ），女，博士，教授，博士生导师。研究方向：天人相应理论与临床。Email：mashuran64@sina.com
更新日期/Last Update: 1900-01-01